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Deep learning Gets a "Toehold" on Synthetic Biology
Two teams of scientists have devised pathways around a synthetic biology roadblock by developing a set of machine learning algorithms that can analyze reams of RNA-based “toehold” sequences and predict which ones will be most effective at sensing and responding to a desired target sequence.
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Team Is Working To Develop a Universal Flu Vaccine
Researchers are working on strategies for designing a universal flu vaccine that could work against any flu strain.
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New Platform Tests How Breast Cancer Cells Respond to Stretching
A team from Purdue University has created a new platform to test how breast cancer cells respond to the recurrent stretching that occurs in the lungs during breathing.
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Drug Compound Targets Weakness in Advanced Prostate Cancer
A new study reports that prostate cancer cells with a deletion of the SUCLA2 gene can be therapeutically targeted using the compound thymoquinone.
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Team Identifies Potential Drug Targets for Treatment of Epilepsy
Researchers have now identified the neurons that are most affected by epilepsy – some have never been linked to epilepsy before.
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Jennifer A. Doudna and Emmanuelle Charpentier Win 2020 Nobel Prize in Chemistry
The Royal Swedish Academy of Sciences has decided to award the Nobel Prize in Chemistry 2020 to Emmanuelle Charpentier and Jennifer A. Doudna “for the development of a method for genome editing”.
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Drug Resistance Mechanism in Leukemia Discovered
Leukemia modulates the bone marrow niche to protect and promote the survival of tumor cells. Scientists now show that this protective environment also gives leukemia cells with insufficient expression of BRCA1 and BRCA2 genes the ability to resist a specific type of anticancer drug called PARP inhibitors.
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Mysterious Molecular Concept Could Be Used To Target Diseased Cells With High Specificity
Researchers have demonstrated how a mysterious molecular concept named "range selectivity" could be used to target diseased cells with high specificity.
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Drug for Aggressive Childhood Cancer Shows Promise in Preclinical Study
A drug has shown promise in the treatment of neuroblastoma, an aggressive form of childhood cancer. The study involved treating mice with the drug, the KSP inhibitor prevented tumor growth and prolonged survival.
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Technique Identifies Optimized Combinations of Anticancer Drugs
Scientists from the University of Geneva (UNIGE) have developed a technique for quickly identifying from a large number of existing drugs the optimal synergistic combination and dose of products that can kill tumour cells without affecting healthy cells.
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