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The U.S. Food and Drug Administration (FDA) has granted Fast Track designation to a novel “switchable” CAR T-cell therapy developed by Calibr, a division of Scripps Research, in a move to accelerate the drug development and review process.

Experts working in the field of vaccine development tend to believe that an effective vaccine is not likely to be available for the general public before the fall of 2021. In a paper published recently in the Journal of General Internal Medicine, a McGill-led team published the results of a recent survey of 28 experts working in vaccinology.

Scientists at Scripps Research have mapped how a key class of proteins within cells regulates signals coming in from cell surface receptors. The study has discovered that people commonly have variants in these proteins that cause their cells to respond differently when the same cell receptor is stimulated.

Outer ear infections affect millions of people every year. Repeatedly administering antibiotic drops can be a problem for some people and the only single-use suspension currently available needs to be kept and handled cold. Researchers have now developed a single-use treatment that doesn’t require refrigeration.

A Phase 1 trial of an investigational mRNA vaccine to prevent SARS-CoV-2 infection has shown that the vaccine is well-tolerated and generates a strong immune response in older adults.

Women vaccinated against HPV have a significantly lower risk of developing cervical cancer, and the positive effect is most pronounced for women vaccinated at a young age. That is according to a large study by researchers at Karolinska Institutet in Sweden.

A team of scientists has identified small molecules that are able to target the RNA genome of SARS-CoV-2, the coronavirus responsible for COVID-19. The molecules interfere with viral gene expression and consequently target the RNA for destruction.

Researchers from The University of Texas at Austin have uncovered problems with the conventional method for growing organoids for common experiments that may cause misleading results.

Young researchers with an advanced degree can apply for the highly prestigious Eppendorf Award for Young European Investigators that acknowledges outstanding contributions to biomedical research in Europe .

As Parkinson's disease progresses, more levodopa is required to treat it. Too much, however, can lead to uncontrollable, involuntary bodily movements. To better understand the underlying reasons behind these effects, researchers created a model of the interactions between levodopa, dopamine, and the brain.