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“plasmaMATCH” Trial Matches Female Breast Cancer Patients to Precision Treatments Using Blood Test
A blood test that can identify a variety of mutations in advanced breast cancer can reliably match women to effective targeted treatments, according to results from a new clinical trial.
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Antibiotic Molecule Enables HIV Infected Cells To Be Killed by the Immune System
A class of antibiotic molecules called pleicomacrolides inhibit the Nef protein, which HIV uses to evade the body's immune system, leaving open to immune clearance.
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CombiGene and Cobra Biologics Sign Gene Therapy Production Agreement
The agreement is part of preparations for GMP production of material for the first clinical study of CG01.
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A New Way To Limit Inflammation From Adjuvants
Researchers at the Pritzker School of Molecular Engineering (PME) at the University of Chicago have discovered a new way to limit inflammation from adjuvants: by adding a molecule that disrupts certain pathways in cells.
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A Novel Tool for Predicting Order and Disorder in Proteins
In their new paper, researchers have used machine learning together with experimental NMR data for hundreds of proteins to build a new bioinformatics tool called ODiNPred. This bioinformatics program can help other researchers making the best possible predictions of which regions of their proteins are rigid and which are likely to be flexible.
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Convalescent Plasma Appears Safe and Possibly Effective in Pediatric Patients With Severe COVID-19
Early findings from a small study indicate that convalescent plasma appears to be safe and possibly effective as a treatment for children with life-threatening cases of COVID-19.
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Artificial Intelligence Identifies DNA Activation Code
With the help of artificial intelligence, researchers at the University of California San Diego have identified a DNA activation code that’s used at least as frequently as the TATA box in humans.
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Synthetic Antiviral Proteins Inhibit SARS-CoV-2 in Lab-Grown Human Cells
Researchers have designed and developed proteins that bind tightly to the SARS-CoV-2 Spike protein, preventing the virus from infecting lab-grown human cells.
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A Better Understanding of How Metformin Works in the Body
Researchers at the Salk Institute have demonstrated the importance of key enzymes in the body for metformin's function. In addition, they showed that the same enzymes, regulated by metformin, controlled aspects of inflammation using a mouse model.
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A New Way To Target Rapidly Dividing Breast Cancer Cells
Scientists have discovered a new way to kill some multiplying human breast cancer cells by selectively attacking their cell division machinery.
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