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Chemists have used molecular modeling to identify two existing drugs that could be used to fight SARS-CoV-2. These are disulfiram, which is used to treat alcoholism, and neratinib, an experimental drug being used to treat breast cancer.

A drug candidate previously shown to slow aging in brain cells has successfully reversed memory loss in a mouse model of inherited Alzheimer’s disease.

Researchers have developed a new mouse model to study SARS-CoV-2 infection and disease and to accelerate testing of novel treatments and vaccines against the novel coronavirus.

Biomedical engineers have developed a method for controlling the phase separation of an emerging class of proteins to create artificial membrane-less organelles within human cells.

Researchers have developed new models to study the molecular characteristics of lung and pancreatic tumors that are driven by mutations in the NTRK1 gene.

By applying “temporal pressure” to the skin of mice, researchers have shown that the pressure technique can be used to create a novel drug delivery approach.

Scientists have developed a highly selective and highly stable synthetic blood-thinning molecule that, unlike others, doesn’t cause bleeding adverse effects.

A Phase 2 clinical trial will evaluate the safety and efficacy of potential new therapeutics for COVID-19, including an investigational therapeutic based on synthetic monoclonal antibodies (mAbs) to treat the disease.

A clinical trial of RLF-100 (aviptadil) has shown rapid recovery from respiratory failure in critically ill patients with COVID-19.

Four stranded DNA structures called G-quadruplexes have been shown to play a role in certain types of breast cancer, providing a potential new therapeutic target.