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Targeted Therapy Shows Effectiveness in Skin Disease Patients

Mayo Clinic researchers have identified a targeted therapy that could bring relief to people living with lichen planus, a chronic inflammatory skin condition of the skin, hair, nails, mouth and genitals.
A human brain.
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Low Doses of Oral Ketamine Can Reduce PTSD Symptoms, Study Suggests

A new study finds that oral ketamine significantly reduces PTSD symptoms, with 73% of participants seeing a 50% reduction in symptoms. The treatment, taken as a liquid drink, was well-tolerated and had fewer side effects than intravenous ketamine.
A blue and red capsule split in two.
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How an Effective Cancer Therapy Was Redesigned To Make It Safer

UIC researchers have redesigned asparaginase, a key leukemia treatment, to reduce severe side effects like liver damage and blood clots. The modified enzyme is more effective and may treat other cancers like melanoma.
Two medicinal tablets, one broken in half
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Digoxin Could Save Millions a Year Treating Common Heart Rhythm Disorder

A 240-year-old drug called digoxin could save the National Health Service (NHS) at least £100 million each year when treating older patients with atrial fibrillation and heart failure.
Various painkiller tablets and capsules scattered on a dark surface.
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US Approves Non-Opioid Painkiller: What Is It, and How Does It Work?

The US Food and Drug Administration (FDA) announced its approval of a non-opioid treatment for moderate–severe acute chronic pain. The drug, Journavx™ (suzetrigine), represents the first new class of pain management medicine to be approved in the US.
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Antibody Treatment Protects Monkeys Against Severe Bird Flu

A prophylactic antibody-based immune therapy has been shown to protect monkeys against severe bird flu caused by H1N1.
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AI Can Help Boost Cancer Treatment Efficacy, But Doctors Remain Key

A study from Moffitt Cancer Center and the University of Michigan shows that AI-assisted radiotherapy can help doctors make more consistent treatment decisions for lung and liver cancer. However, doctors' trust in AI recommendations varies.
Cancer cells.
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Pre-Operative Radiotherapy May Hamper Breast Cancer Immunotherapy

Researchers found that radiotherapy may reduce immune cells in the tumor-immune microenvironment, potentially impacting immunotherapy success. The study challenges the assumption that radiotherapy turns “cold” tumors “hot.”
The marrow-on-a-chip system, held in a researcher's hands.
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Engineered Marrow-on-a-Chip Successfully Emulates Human Bone Marrow

A platform that emulates human marrow's native environment has helped researchers to recreate human marrow's complexity.
A drug capsule.
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Antibiotic Resistance Can Develop Before Drugs Hit the Market

Scientists in Hungary found that antibiotic resistance can emerge before new drugs are even in clinical use. The study highlights pre-existing bacterial mutations that render new treatments ineffective.
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