New Tuberculosis Vaccine Passes Safety Test
A new vaccine for tuberculosis has been shown to be safe for newborns and has fewer side effects than the current vaccine.
Genetic Risk Factors for Opioid Use and Related Substance Use Disorders
A new human genomics study led by Yale scientists has identified genetic risk factors for opioid use disorder (OUD) and related substance use disorders according to a new large-scale genome-wide association study – increasing the number of risk genes known from 1 to 19.
Targeted Immunotherapy Developed for Direct Injection Into Tumors
A new method of delivering an immunotherapy directly to a tumor has been developed, composed of a gelatin/nanoplatelet mixture for effective drug delivery and sustained drug release.
Cancer Cells Release “Drones” To Block the Immune System
Researchers found a mechanism by which cancers keep T cells from infiltrating tumors by sending out exosome "drones", which offers a new tool to predict how a patient might respond to checkpoint inhibitor drugs.
Weak Spot in Leukemia Cell Death Pathways Could Lead to New Therapies
According to a study, epigenetic changes prevent iron-associated programmed cell death in leukemia and show a new target for treatment with experimental drugs.
Signaling Pathway Indicates Link Between Esophageal Cancer and Barrett's Syndrome
Researchers believe they have identified a cell signaling pathway responsible for the development of an aggressive and increasingly common form of esophageal cancer, which could potentially be used as a therapeutic target.
Study Shows Early Childhood Exposure to Antibiotics Can Cause Asthma and Allergies
A new study has provided strong evidence showing that exposure to antibiotics in early childhood kills healthy bacteria in the digestive tract and can cause asthma and allergies.
New Targeted Therapy an Option for Neuroblastoma Treatment
Researchers have demonstrated that a novel targeted therapy could be an effective treatment option for neuroblastoma, a deadly pediatric cancer.
Gene Responsible for Deadly Brain Tumors Also Causes Childhood Cancers
Researchers have identified that the gene responsible for glioblastoma also drives the development of soft tissue cancers in children.
Vaccine Patch Fights COVID Variants Better Than Needles in Mouse Model
According to a murine study, a needle-free vaccine patch could better fight COVID-19 variants than a traditional needle vaccine.