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Shaping Cells With Light

Imagine switching on a light and being able to understand and control the inner dynamics of a cell. By shining lights of different colors on replicates of cells, researchers altered the interactions between cellular elements.
Escherichia coli under a microscope.

Novel Antibiotics Combat Drug-Resistant Bacteria

Scientists at Uppsala University have discovered a new class of antibiotics with potent activity against multi-drug resistant bacteria, and have shown that it cures bloodstream infections in mice.
White pills on a blue background.

Study Sheds Light on Side Effects for Children Taking Asthma Drug

A University of Oklahoma study about a “black box warning” for the asthma drug Singulair continues to influence a national conversation about the medication and its reported neuropsychiatric side effects in children and adolescents.
An image of tert-butane, the simplest quaternary carbon.

A New, Cost-Effective Method for Producing Quaternary Carbon Molecules

The active ingredient in many drugs is what’s known as a small molecule: bigger than water, much smaller than an antibody and mainly made of carbon. Scripps scientists have uncovered a potential cost-effective way to produce these tricky motifs.
A stool sample.

Stool Transplant Improves Motor Function in Parkinson's Disease Patients

Fecal microbiota transplantation improves motor symptoms in Parkinson’s disease patients after 12 months. That's according to data from the GUT-PARFECT trial that recruited 46 Parkinson's disease patient.
Drug molecules spilling out of a blue and red capsule.

“Click” Chemistry Helps To Create Over 150 Potential Drug Compounds

Chemists have created a new collection of molecular compounds and begun testing them as potential leads in the search for new drugs. Among these molecules, they found several that show promise for development as antibiotics and cancer therapies.
3-D printed objects.

Biodegradable Aerogel: Airy Cellulose Materials From a 3D Printer

Empa researchers have succeeded in 3D printing the natural material into complex shapes that could one day serve as precision insulation in microelectronics or as personalized medical implants.
Embryonic stem cells

CAR-MSCs Could Treat a Broad Spectrum of Autoimmune Diseases

Mayo Clinic scientists have developed an immunotherapy strategy that utilizes CAR-MSCs. The approach shows potential in targeting inflammatory disease sites more precisely and improving immunosuppression and healing outcomes.
A digital image of a brain with multicolored threads emerging from it.

Diabetes Drug Shows Promise for Parkinson’s Disease in Trial

Results from a Phase 2 clinical trial suggest that lixisenatide – a drug used to treat type 2 diabetes – may also slow the progression of Parkinson’s disease symptoms.
Vaccine vials.

Designing a Vaccine To Block “Zombie Drug” Xylazine

Scripps Research chemical biologists have developed a vaccine to block the effects of xylazine’s toxicity. The vaccine works by training the immune system to attack the drug, which is described in a new paper published in Chemical Communications.