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Synthesized Fungal Molecule Reactivates Self-destruct Gene in Cancer Cells
A research team has developed a method to artificially produce a fungal compound capable of rearming the self-destruct gene in certain cancer cells, providing a potential cancer therapeutic strategy.
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Our Gut Microbes May Chemically Transform Medication Impacting Drug Safety and Efficacy
Researchers have developed a systematic approach for evaluating how our gut microbiome can chemically transform oral medications in ways that impact their safety and efficacy.
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New Genetic Testing Recommendations for Prostate Cancer
Key recommendations, which were published in the Journal of Clinical Oncology, include a strong endorsement to perform genetic testing of all men with metastatic prostate cancer to inform precision medicine or clinical trial eligibility.
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Microneedling Therapeutic Stem Cells Into Damaged Tissues
Small and minimally invasive "Detachable Microneedle Depots" effectively deliver stem cells for localized MSC therapy of skin disorders.
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Anti-histamines Could Rebalance Dopamine Signaling in Huntington's
Controlling dopamine signaling by targeting the histamine receptor could be a promising strategy for preventing the progression of Huntington’s disease in mice, according to a new study.
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Chemo Not the Only Culprit in Neuropathy – Cancer Itself Contributes Too
A new study suggests that chemotherapy might not be the only culprit in neuropathy, a neurological side effect of cancer treatment, cancer itself also contributes heavily.
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New Strategy Induces Stress Inside Tumors Causing Cancer Cell Destruction
A study describes a new strategy for tackling cancer, based on inducing potent stress in tumors, causing cell destruction by autophagy. The mechanism has been investigated using a novel antitumor drug "ABTL0812".
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Many “First-wave” COVID-19 Clinical Studies Have Significant Design Shortcomings, Says Study
Most of the registered clinical trials exploring potential treatments for COVID-19 that are underway as of late March were designed in a way that will greatly limit their value, according to a new study.
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New DNA Replication Insights Can Be Applied To Develop Novel Cancer Therapies
Researchers have uncovered further insights into how the replication of DNA occurs, which could be applied to help develop novel cancer treatments.
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Large Study Suggests Blood Type O May Be a Protective Factor Against COVID-19
23andMe are in the process of conducting a large-scale genetic study to explore whether genetics are implicated in susceptibility to and severity of COVID-19. The company has shared its preliminary results.
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