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MERS Vaccine Clinical Trial Offers Useful Insights for SARS-CoV-2 Vaccine Development
A first-in-human trial of a vaccine against “MERS” (Middle East Respiratory Syndrome) has been conducted, and offers lessons and insights for the development of a SARS-CoV-2 vaccine.
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Touch Restored to Spinal Cord Injury Patient Using Brain-Computer Interface
Researchers report that they have been able to restore sensation to the hand of a research participant with a severe spinal cord injury using a brain-computer interface (BCI) system.
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First New Oral Polio Vaccine in 50 Years Offers Lessons for COVID-19
Researchers have redesigned the polio vaccine to ensure that is incapable of following a three-step pathway to re-evolve virulence.
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Pediatric Oncology Clinical Trial Enrollment Down
A new study shows pediatric oncology clinical trial enrollment may be down, from 40-70 percent seen in studies completed in the 1990s, to 20-25 percent in the early 2000s, to 19.9 percent in the current study.
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COVID-19 Testing Service Center To Evaluate Promising Drugs
Northern Arizona University's Pathogen and Microbiome Institute has announced that it is launching a COVID-19 Testing Service Center to grow the SARS-CoV-2 virus and test new drugs against it.
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UAB Team Joins Search for Drugs Effective Against COVID-19
Researchers from University of Alabama at Birmingham will screen a repurposed library of compounds to determine if any licensed drugs have activity against SARS-CoV-2, the novel coronavirus that causes COVID-19.
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NIAID Plan Details COVID-19 Research Priorities
A new strategic plan from the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health, details the institute’s plan for accelerating research to diagnose, prevent and treat COVID-19.
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Diabetes Reversed in Mice With CRISPR-edited Stem Cells From Patients
Using induced pluripotent stem cells produced from the skin of a patient with a rare, genetic form of insulin-dependent diabetes called Wolfram syndrome, researchers transformed the human stem cells into insulin-producing cells and used the gene-editing tool CRISPR-Cas9 to correct a genetic defect that had caused the syndrome.
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New Microneedle Array Combination Vaccine Delivery System
Novel vaccine delivery technology will contribute to efforts to develop universal vaccines and improve global immunization capabilities essential for combating coronavirus, reports the Journal of Investigative Dermatology .
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It Could Be Left to Doctors To Notice Rare Drug Side Effects Post-approval
As drugs more precisely target cancer subtypes, clinical studies designed to test these drugs are enrolling fewer patients. Smaller studies reduce the likelihood of uncovering rare side effects, and so it may fall on clinicians using these drugs after FDA approval to notice medication side effects that went undetected during clinical trials.
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