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Supercomputers Figure Out How Viruses Attack Cell Membranes
Fundamental research supported by supercomputers could help lead to new strategies and better technology that combats infectious and genetic diseases.
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Phase 2 Trial Shows Selumetinib Shrinks Nerve Tumors in Children With NF1
A Phase 2 clinical trial shows that the drug selumetinib improves outcomes for children with the genetic disorder neurofibromatosis Type 1 (NF1).
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Minor Modification to Botox May Boost Binding and Improve Safety
A new study reports that a subtle modification made to an FDA-approved form of botulinum toxin enhances binding to nerve cells and increases the drug's potency and safety.
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Using Organs-on-Chips To Model Complicated Diseases
MIT biological engineers have created a multitissue model that lets them study the relationships between different organs and the immune system, on a specialized microfluidic platform seeded with human cells.
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Phase II Trial of SNG001 in Coronavirus Patients Set To Start
Synairgen has received expedited approvals from the Medicines and Healthcare products Regulatory Agency and Health Research Authority to conduct a trial of SNG001 in COVID-19 patients to potentially help with the global outbreak of the virus.
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Blocking Sugar Structures on Viruses and Cancer Cells
Researchers have created a new type of protein reagent for identifying biological sugar structures, which may block the spread of an illness in the body if used for blocking the sugar structures of a cell or a virus.
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Bacterial Enzyme A Potential New Target for Antibiotics
Chemists have discovered the structure of an unusual bacterial enzyme that can break down an amino acid found in collagen, which could provide a target in treating C. difficile infections.
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New IL-2 Insights Guide Drug Discovery Efforts
A team has figured out the details of interleukin-2 (IL-2)’s complex interactions with receptor molecules on immune cells, providing a blueprint for the development of more targeted therapies for treating cancer and autoimmune diseases.
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Egg-derived Bioinks for Organ Engineering
Researchers have developed a new vascular supportive composite bioink using marine algae (alginate) and egg while (albumen), which could be used to 3D print a vascular supportive organ structure.
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Drug Candidate Could Deliver More Cancer-busting Power Than Chemo
A drug candidate has been found in preclinical studies to stop tumor growth entirely, delivering more cancer-busting power than many commonly used chemotherapy drugs and with fewer side effects.
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