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Too Much of a Good Thing May Lead to Too Much of a Liver
A team of scientists suggest prolonged exposure to NRF2 and KEAP1 may contribute to enlargement of the liver and fatty liver diseases.
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Living Cell Imaging Approach Sheds Light on Obesity
Utah State University researchers have developed probes to help improve techniques to test drugs for obesity-related conditions.
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Team Designs Tiny Nanoparticles To Target Cancer Cells
Scientists have designed tiny nanoparticles that can specifically navigate to, and target, cancer cells.
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Functional Studies Aid Fight Against Parasitic Diseases
In the quest to develop more effective treatments for parasitic diseases like African sleeping sickness, Chagas disease and Leishmaniasis, scientists look for weaknesses in the organisms’ molecular machinery. These weaknesses can then be targeted with drug therapies designed to kill the parasites.
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Checkpoint Inhibitors for Cancer Can Activate TB Infection
Researchers at the University of Southampton have discovered that new checkpoint inhibitor treatments for cancer are capable of activating tuberculosis in some patients.
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Hunting Hibernating Breast Cancer Cells in the Lung
Researchers from The Francis Crick Institute have discovered that lung cancer cells can support the survival of breast cancer cells, allowing them to hibernate inside the lung before they begin to form secondary tumors.
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Can "No Raw Data, No Science" Improve Reproducibility?
The 'reproducibility crisis' has become a significant issue in modern science and one journal editor has penned an article suggesting that, for journals, a "no raw data, no science" approach to article approval may be required to avert further damage to the scientific method.
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Brain Organoid Study Shows Antidepressant Harms Developing Neurons
Researchers have uncovered that an antidepressant may harm developing neurons; the use of a brain organoid could pave the way for their use in wider testing of developmental toxicity.
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Shaping the Rings of Molecules
Scientists report that they have succeeded in using a natural process called biocatalysis to control the shapes of macrocycles. These molecules can be used to create pharmaceutical and electronics.
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Switch Up Heart Cell Diet To Help Regeneration
Switching what the powerhouses of heart cells consume for energy could help the heart regenerate when cells die, a new study led by UT Southwestern researchers suggests.
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