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How AI-Powered Cell Culture Could Revolutionize Drug Discovery
Shantanu Dhamija discusses how AI can help scientists to fully embrace organoids in drug discovery.
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Targeted Cancer Therapy Shows Promise Combined With Cholesterol-Lowering Drug
A novel therapeutic approach that combines human epidermal growth receptor factor 2 (HER2)-targeted therapies with the cholesterol-lowering drug lovastatin can reduce the number of cancer treatments required to prevent tumor growth.
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Drug Shows Promise for Restoring Parathyroid Function in Small Trial
An investigational drug restored calcium levels in people with autosomal dominant hypocalcemia type 1 (ADH1), as well as abnormally low levels of parathyroid hormone, which regulates blood calcium levels.
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Study Uncovers Why Young Children Suffer Less Severe COVID-19
A study of infants and young children found those who acquired SARS-CoV-2 had a strong, sustained antibody response to the virus and high levels of inflammatory proteins in the nose but not in the blood.
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Targeting Cellular Stress-Controlling Gene Suppresses Brain Cancer Growth in Mice
Researchers have identified a gene that links cancer cells’ ability to cope with DNA replication stress to cancer growth, also highlighting a potential strategy to combat aggressive brain cancers like glioblastoma.
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Novel Drug Prevents Development of Common Skin Cancer in Mouse Study
A preclinical study shows that a new drug that can be applied to the skin prevents the development of the second most common type of skin cancer.
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Methotrexate Improves Hand Osteoarthritis Symptoms
Relief could be on the way for people with painful hand osteoarthritis after a Monash University and Alfred Health-led study found an affordable existing drug can help. Until now there has been no effective treatment.
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200-Year-Old Fly DNA Unveils Iconic Lab Animal's Genetic History
The humble fruit fly is one of the most thoroughly studied animals on the planet and new insights continue to be revealed about the fly’s evolution thanks to centuries-old DNA.
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New Test Accurately Measures Biological Aging in a Clinical Setting
Researchers have developed a "clock" that accurately measures biological aging in healthy and diseased tissue. They used the clock to better understand the impact of different treatment options for kidney disease.
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Blocking Immune Molecule Prolongs Survival in Models of the Most Aggressive Childhood Cancer
Researchers have confirmed that blocking an immune control molecule reduces the tumor and prolongs survival in animal models of aggressive childhood cancer.
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