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New NMR-based Method Simplifies Natural Product Structural Analysis
Many drugs are derived from natural products. But before natural products can be exploited, chemists must first determine their structure and stereochemistry. A new NMR-based method has now been developed that simplifies the analysis and produces more accurate results.
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Antiviral “Surprise” Inspires a New Kind of Cancer Drug
Researchers have discovered that by disrupting otherwise normal cellular processes that both viruses and some cancer cells rely on to grow and spread, it is possible to shrink tumors and prevent their spread, in mouse models of cancer.
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Capsule Innovation Could Make Treating Phenylketonuria Easier
Scientists have developed a stable capsule shell for the enzyme needed to treat phenylketonuria, which could make treatment of the disease easier.
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CRISPR Cuts Open New Avenues in CAR T-cell Therapy
According to a study published in the Blood journal, drug profiling and the CRISPR-Cas9 gene editing method have opened new avenues in the development of CAR T-cell therapy, used to treat leukaemia and lymphoma.
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Potential Therapeutic Target for Alzheimer's
A previously unknown gene and associated protein which could potentially be suppressed to slow the advance of Alzheimer’s have been discovered, presenting a potential therapeutic target to combat the disease.
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Zebrafish Makes Scientists Think Twice About Atrial Fibrillation
A new study in zebrafish suggests a possible link between a genetic variation and a common type of cardiac arrhythmia, atrial fibrillation.
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Drug Combo Reverses Osteoarthritis in Rats
Salk researchers have discovered that a combination of two experimental drugs reverses the cellular and molecular signs of osteoarthritis – in rats and in isolated human cartilage cells.
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Compound Awakens Cancer Cells’ Self-destruct System
Researchers develop a compound that, in mice, awakened cancer cells’ "self-destruct" process, killing the cancer cells and consequently stopping their spread, while leaving "normal" cells untouched.
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Global Efforts To Contain Antibiotic Resistant Infections Under Threat
According to the World Health Organization, a weak development pipeline for new antibiotics is undermining efforts to combat drug-resistant infections.
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Progression of Eye and Cardiac Disease Halted by Food Supplement
UNIGE researchers have discovered a new gene that causes blindness and
cardiomyopathy. They have also managed to halt the progression of eye disease and treat cardiac disease by administering a food supplement.
cardiomyopathy. They have also managed to halt the progression of eye disease and treat cardiac disease by administering a food supplement.
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