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Doubt Cast on the Use of Viagra for Fetal Therapy
University of Manchester scientists investigating a possible treatment for fetal growth restriction (FGR), a condition in which babies grow poorly in the womb, have urged further caution on the use of Viagra.
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Why Can’t Bertrand Might Cry? Missing Water Channels Could Be the Answer
Scientists have shown that cells from children with NGLY1 deficiency--a rare disorder first described in 2012--lack sufficient water channel proteins called aquaporins. The discovery may help explain the disorder's wide-ranging symptoms--including the inability to produce tears, seizures and developmental delays--and opens new avenues to find therapies to treat the disorder.
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Could B Cells Be the New Allies in Sarcoma Immunotherapy?
New research published in Nature suggests that B cells also play a major role in predicting of patient’s response to immunotherapy, whilst it was previously thought only T cells could be used in this way.
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Scientists Breach Brain Barriers To Tackle Tumors
Yale researchers have discovered a novel way to evade the brain’s natural defenses by slipping immune system “rescuers” through its drainage system.
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Team Develops New Nanoparticle Drug To Treat Aggressive Breast Cancer
Researchers have engineered and tested a new therapeutic nanoparticle platform to deliver the drug paclitaxel to treat triple-negative breast cancer.
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Drug Interaction Insights May Help Design Better Malaria Treatments
Researchers report in the journal Nature that they have for the first time demonstrated at the molecular level what happens when two antimalarial drugs were combined.
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A Novel Target for Drug Addiction Treatment?
Researchers from University of Minnesota Medical School have discovered a novel potential target for treating drug addiction through astrocytes which they refer to as “the hidden stars of the brain.”
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Study of Over 170,000 Individuals Identifies Genes Associated With High Alcohol Consumption
In a new research study published in the journal Science Advances, scientists from the University of Liverpool sought to identify specific genes that are associated with high levels of alcohol consumption.
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Small Molecule Promises Treatment for Alzheimer's and Dravet Syndrome
Researchers have shown the therapeutic efficacy of a new experimental drug in mouse models of Alzheimer’s disease and a rare genetic form of epilepsy known as Dravet syndrome.
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A Biomaterial-based Vaccine for Blood Cancer
An injectable, biomaterial-based vaccine, when combined with standard chemotherapy, resulted in the complete and lasting recovery from, and immunity against, the deadly blood cancer acute myeloid leukemia (AML) in mice.
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