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Methotrexate Improves Hand Osteoarthritis Symptoms

Relief could be on the way for people with painful hand osteoarthritis after a Monash University and Alfred Health-led study found an affordable existing drug can help. Until now there has been no effective treatment.
A fruit fly in a leaf.
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200-Year-Old Fly DNA Unveils Iconic Lab Animal's Genetic History

The humble fruit fly is one of the most thoroughly studied animals on the planet and new insights continue to be revealed about the fly’s evolution thanks to centuries-old DNA.
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New Test Accurately Measures Biological Aging in a Clinical Setting

Researchers have developed a "clock" that accurately measures biological aging in healthy and diseased tissue. They used the clock to better understand the impact of different treatment options for kidney disease.
Cancer cells.
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Blocking Immune Molecule Prolongs Survival in Models of the Most Aggressive Childhood Cancer

Researchers have confirmed that blocking an immune control molecule reduces the tumor and prolongs survival in animal models of aggressive childhood cancer.
A man spreading pesticides onto a field of yellow mustard flowers.
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Popular Herbicide Ingredient Linked to Chronic Kidney Disease Epidemic in Sri Lanka

The active ingredient in Roundup, the world’s most popular herbicide, may play a role in the epidemic levels of chronic kidney disease seen in rural Sri Lanka, a new study suggests.
A lab mouse.
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New Experimental Method Reduces the Number of Laboratory Animals Needed

To study muscle diseases, scientists rely on mice as a model organism. Researchers have now developed a new method that is not only faster and more efficient than conventional ones but also greatly reduces the number of experimental animals needed.
Pills in a box.
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Americans May Take Prescription Drugs for Around Half Their Lives

A new study examining trends in prescription drug use in the US suggests that Americans born in 2019 are expected to take prescription medications for roughly half their lives.
A single dark blue and pink drug capsule on a light blue background.
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Metformin May Help Us Treat Gum Disease and Age Healthier, Study Suggests

Metformin could be used to control inflammation and sugar levels in both the mouth and body, helping us to age healthier and to treat gum disease.
A plastic model of a pair of lungs, bisected to show the internal structures.
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Synthetic Molecules Help Clear Cystic Fibrosis Mucus Blockages

A University at Buffalo-led research team has developed molecules that could help unclog thick, sticky mucus from the lungs of people suffering from cystic fibrosis.
Vaccine glass vials.
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Can Immunity From Childhood Vaccines Be Harnessed To Fight Cancer?

A University team has demonstrated in theory that a protein antigen from a childhood vaccine can be delivered into the cells of a malignant tumor to refocus the body’s immune system against the cancer.
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