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Targeting a Protease To Treat Inflammatory Bowel Disease
The protease MT1-MMP could be a possible future target for drugs to treat inflammatory bowel disease (IBD) according to a new study.
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Detecting Potential Anticancer Compounds That Reawaken T Cells
Researchers have developed a method for rapidly discovering potential cancer-treating compounds that work by "resurrecting" the anti-tumor activity of T cells.
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Investigating the Human Intestinal Mucus Barrier Up-close and Personal
Personalized medicine approach using a human Colon Chip opens up gateway to study mucus barrier functions in patients with intestinal diseases in vitro.
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When Data Says "Stop"
A research team led by Northwestern Engineering's Luis Amaral has developed an algorithmic approach for data analysis that automatically recognizes uninformative words -- known as stop words -- in a large collection of text.
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Taste Proteins Could Point Way to Alzheimer's Drugs
Research has revealed the near-atomic level structure of a protein that plays a key role in processing taste stimuli and moderating toxicity in brain cells.
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Treatment Could Help the Clearance of Kidney Stones
A team has identified a combination of two drugs that work to relax the walls of the ureter — and can be delivered directly to the ureter with a catheter-like instrument. Relaxing the ureter could help kidney stones clear more easily.
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A Nice Reactive Ring to It
Researchers have introduced a new synthetic process for producing an important family of carbon-based molecules known as γ-aryl-β-ketoesters. These molecules are used in the production of many vital pharmaceuticals.
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Harnessing Higher-energy Light To Combat Cancer
Materials scientists have shown that it is possible to achieve photon up-conversion, – the emission of light with energy higher than the one that excites the material. This development brings scientists a step closer to developing minimally invasive photodynamic cancer treatments,
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Triggering the Self-destruction of Pancreatic Cancer Cells
A newly published study shows that a small molecule has the ability to induce the self-destruction of pancreatic cancer cells.
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Ribosome-based Treatments: A Sought After Therapy Option for Orphan Diseases?
Recently, Urania Therapeutics announced that it has successfully raised €3.53M ($3.89M) in seed funding to unlock the therapeutic potential of ribosome-based treatments. We spoke with Jean-Paul Renaud, President and CSO of Urania Therapeutics, to learn more about the mechanisms of readthrough compounds and how the company hopes to provide treatment solutions for orphan diseases.
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