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Tucatinib Against Stage IV HER2+ Breast Cancer, Phase III Trial Results Promising
Study results show that the combination of the investigational drug tucatinib with standard of care treatment (including the drugs trastuzumab and capecitabine) nearly tripled one-year progression-free survival (33% vs. 12%), and nearly doubled the two-year overall survivor (45% vs. 27%) in women with HER2+ metastatic breast cancer.
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Study Reveals How Pancreatic Cancer Cells Avert Starvation
Researchers have revealed the mechanism that helps pancreatic cancer cells avoid starvation within dense tumors – they hijack a process that pulls nutrients in from their surroundings.
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Therapy Tested in Mice Shows Potential Against Leukemias
A promising new approach to treating some of the worst types of leukemia, including an aggressive leukemia that mostly affects babies has been discovered.
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Blood Pressure Drug May Help Ease Anxiety Induced by Long-term Heavy Alcohol Use
A new study suggests that a drug used to treat high blood pressure may alleviate anxiety caused by long-term heavy alcohol use, and may also halt the damage such drinking can cause to the brain’s ability to grow new cells.
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How To Hide Data in Everyday Objects
Researchers have developed a means of storing extensive information in almost any object. The way of storing this information is the same as for living things: in DNA molecules.
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First-of-a-Kind In Vitro 3D Neural Tissue Model Developed
Researchers at the University of Illinois at Urbana-Champaign have successfully used stem cells to engineer living biohybrid nerve tissue to develop 3D models of neural networks with the hopes of gaining a better understanding of how the brain and these networks work.
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Criteria for Cancer Clinical Trials Might Be Too Strict
Federal regulations may be keeping lung cancer patients out of clinical trials simply because the patients are on medications that might affect the electrical system of the heart. The regulations may be preventing al proportion of patients from participating in clinical trials.
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“Scar in a Dish” Model Mimics Fibrosis
A team has developed a “scar in a dish” model that uses multiple types of cells derived from human stem cells to closely mimic the progressive scarring that occurs in human organs. The researchers used this model to identify a drug candidate that stopped the progression of and even reversed fibrosis in animal models.
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30% of Patients Taking Opioids Face Adverse Drug Interactions
Patients who do not disclose use of other medications are at an increased risk of adverse drug interactions and addiction, according to a new study. The authors estimate that approximately 30% of patients experience such interactions; however, very few are detected and reported.
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CAGEs Lock Up Fats To Treat Obesity in Mice
A new, orally administered liquid has been found to reduce weight in rats fed high-fat diets without causing side effects, pointing to a potential treatment for obesity.
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