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Increased Ventricular Arrhythmias and No Improvement in Death Rate for COVID-19 Patients Who Received Hydroxychloroquine
News   May 23, 2020

A research team led by investigators from Brigham and Women’s Hospital has evaluated real-world evidence related to outcomes for COVID-19 patients who were treated with hydroxychloroquine or chloroquine analogues (with or without a macrolide). The research findings are published in The Lancet.

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Converting Autoimmunity Drugs Into Powerful Anticancer Treatments
News   May 22, 2020

A team from the University of Southampton has discovered a way to transform antibody drugs previously developed to treat autoimmunity into antibodies with powerful anti-cancer activity through a simple molecular “switch”.

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Cell Culture Systems for Anticancer Drug Screening
News   May 22, 2020

A newly published paper provides an insight into in vitro based testing of anticancer drugs.

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Stopping "Cytokine Storms" May Reduce Severe COVID-19 Symptoms
News   May 22, 2020

A clinical trial in people with COVID-19 is testing a drug that may halt an overactive immune response known as "cytokine storms" before it ramps up.

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Olaparib Approved as Gene-targeted Medicine for Prostate Cancer
News   May 21, 2020

Olaparib is a precision medicine that works by selectively targeting and killing cancer cells with faulty DNA repair machinery. On May 19, 2020, the Food and Drug Administration (FDA) approved olaparib for adult patients with a specific type of prostate cancer .

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Targeting Non-cancer Cells To Reduce Liver Tumor Growth
News   May 21, 2020

A treatment that uses small molecule drugs to target “senescent” cells known as "senotherapy" has been shown to blunt liver tumor progression in animal models.

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Nanobowls Aid Delivery of Chemotherapy Drugs to Cancer Cells
News   May 21, 2020

Researchers have designed nanobowl-supported liposomes that improve the loading and delivery of cancer drugs.

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Potentially Treatable Mutations Discovered in Subset of Prostate Cancer Patients
News   May 21, 2020

Prostate cancer patients who do not respond well to PSMA-targeted therapy often have potentially treatable mutations in their DNA damage-repair genes, according to newly published research.

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Infection With SARS-CoV-2 Protects Against Re-infection – At Least in Rhesus Macaques
News   May 20, 2020

Two critical questions are whether vaccines will prevent infection with COVID-19 and whether individuals who have recovered from COVID-19 are protected against re-exposure to the virus. Now, a pair of new studies led by researchers at Beth Israel Deaconess Medical Center (BIDMC) suggests the answer to these questions is yes, at least in animal models. Results of these studies were published today in the journal Science.

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How To Improve the Pneumococcus Vaccine
News   May 20, 2020

Pneumococcus experts describe a newly-found capsule—the 100th to be identified since the pathogen was first discovered in the late 19th century. Microbiologist Moon Nahm, M.D., who led the study, said identifying new capsules is critical to keep up with the rapidly changing bacteria and update vaccines that can save lives.

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