Copper Cysteamine Inhibits the Proliferation of Deep-Seated Tumors
Two new papers explore the effects of copper cysteamine, a next-generation cancer photodrug, as a means to reduce radioactive doses and side effects when treating deep-seated tumor cells.
Exploring the Dance of Key Proteins Behind Circadian Rhythms
Using the relatively simple clocks found in fruit flies (Drosophila melanogaster), researchers reveal that the subcellular location of clock proteins and genes fluctuates with the daily passage of time, indicating that spatial information is translated into time-related signals.
Genetic Mutation in Mice and Monkeys Interferes With HIV and Ebola
A nationwide team of researchers has determined how a genetic mutation found in mice and monkeys interferes with viruses such as HIV and Ebola. They say the finding could eventually lead to the development of medical interventions in humans
Fragile X Drug's Failure Might Be Due to Tolerance. Can Research Overcome It?
A study has found that while the brain acquires resistance to continuous treatment with mGluR5 inhibitor drugs, lasting effects may still arise if dosing occurs intermittently and during a developmental critical period
Potential Therapeutic Targets for Sepsis Identified
Researchers have identified molecular biomarkers, pathways and immune cell dynamics associated with sepsis that could be targeted to prevent the condition from leading to death.
Mutation in Gliomas Sensitizes Them to Immunotherapy
According to murine model findings, a single common genetic mutation may hold the key to making immunotherapy more effective against gliomas.
Bioartificial Kidney Successfully Implanted in Preclinical Model
The Kidney Project’s implantable bioartificial kidney, one that promises to free kidney disease patients from dialysis machines and transplant waiting lists, took another big step toward becoming reality, earning a $650,000 prize from KidneyX for its first-ever demonstration of a functional prototype of its implantable artificial kidney.
Pandemic Stress Caused Irregular Menstrual Cycles
A study has found that people who menstruate experienced irregularities in their menstrual cycle because of increased stress during the COVID-19 pandemic
Scripps Scientists Are One Step Closer to Expanding the Genetic Code
By supplementing the synthetic biology toolkit, researchers have developed key components of an expanded genetic code system.
Mutations of Delta and Delta Plus Variants Identified
Research has identified five specific mutations that are far more prevalent in Delta Plus infections compared to Delta infections of SARS-CoV-2.