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Understanding Immune Cell Recruitment Key to STI Vaccine Development
In a study published in Nature Communications, researchers from King’s have shown how skin vaccination can generate protective CD8 T-cells that are recruited to the genital tissues and could be used as a vaccination strategy for sexually transmitted infections.
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Keeping Kids Safe In the "Internet of Things" Era
Children need protection when using programmable Internet computing devices – and Lancaster University scientists have drawn up new guidelines to help designers build in safeguards.
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Plant-based Diet Leads to Crohn’s Disease Remission, Says Case Study
Eating a plant-based diet may be an effective treatment for Crohn's disease, according to a case study published in the journal Nutrients.
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Autism Gene Linked to Changes Occurring Around Symptom Onset
Unlike other gene mutations linked to autism, which are thought to alter brain development before birth, the newly identified changes in brain signaling may occur closer to the onset of autism symptoms in the first years of life, raising hope that a future therapy could be developed.
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A Drug Target for Chemically Induced Parkinson's Disease
The synthetic opioid, MPTP, induces the onset of a form of Parkinson's disease. In a new study, researchers found that an enzyme in the body can metabolize compounds formed in the brain from alkaloids present in certain foods and tobacco into MPTP-like chemicals, triggering a neurodegenerative condition in mice.
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New Way to Deliver Drugs Through the Skin Using “Nanoemulsion” Gels
MIT chemical engineers have devised a new way to create very tiny droplets of one liquid suspended within another liquid, known as nanoemulsions. They also found a way to easily convert the liquid nanoemulsions to a gel when they reach body temperature, which could be useful for developing materials that can deliver medication when rubbed on the skin or injected into the body.
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Cannabidiol Holds Promise as Powerful Antibiotic
New research has found that cannabidiol is active against Gram-positive bacteria, including those responsible for many serious infections, with potency similar to that of established antibiotics such as vancomycin or daptomycin.
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Mystery Solved: Immunosuppressive Drug's Biosynthesis Revealed
Mycophenolic acid (MPA), discovered in 1893, was the first natural antibiotic to be isolated and crystallized in human history, however, the biogenesis of such an old and important molecule was an unsolved mystery for more than a century. Scientists have now cracked this intriguing black box by fully elucidating the biosynthetic pathway of MPA.
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Biomedical Bleeding May Impact Horseshoe Crab Spawning Behavior
Horseshoe crabs that have undergone biomedical bleeding tend to reside in deeper water and approach mating beaches less often, suggesting the reproductive output of female horseshoe crabs may be compromised during the season in which they were bled.
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First Ever Non-invasive Brain-Computer Interface Developed
A team of researchers from Carnegie Mellon University, in collaboration with the University of Minnesota, has made a breakthrough in the field of noninvasive robotic device control. Using a noninvasive brain-computer interface (BCI), researchers have developed the first-ever successful mind-controlled robotic arm exhibiting the ability to continuously track and follow a computer cursor.
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