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Starving Cancer: Drug Drains Melanoma Cells of Their Energy content piece image
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Starving Cancer: Drug Drains Melanoma Cells of Their Energy

Researchers have found that two structurally similar compounds – deguelin and rotenone, naturally occurring pesticides produced by many plant species – interfered with melanoma cancer cells’ metabolism. Further testing with deguelin showed that it inhibited oxygen consumption in the cells’ mitochondria, effectively starving the cells of energy.
Drug Boosts Bone Growth in Children With Dwarfism in Four-year Study content piece image
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Drug Boosts Bone Growth in Children With Dwarfism in Four-year Study

Researchers report that an experimental drug called vosoritide, allowed the average annual growth rate to increase in a study of 35 children and teenagers with a form of dwarfism. The average boost in height per year was ~6 centimeters (2.4 inches) which is close to growth rates among children of average stature.
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Bitcoin Has a Bigger Carbon Footprint Than Sri Lanka

Researchers have conducted the first analysis of Bitcoin power consumption based on empirical data. They found that the cryptocurrency's carbon emissions measure up to those of Kansas City--or a small nation. The study suggests that cryptocurrencies contribute to global carbon emissions, an issue that must be considered in climate change mitigation efforts.
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Algorithm Tells Robots Where Humans Are Headed

Improvements to a prediction algorithm used in a car manufacturing plant could help robots and humans work better together when sharing the same floor space, whilst maintaining efficiency.
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Cellular Component That Contributes to Lyme Arthritis Uncovered

Biochemist Brandon Jutras has discovered the cellular component that contributes to Lyme arthritis, a debilitating and extremely painful condition – the most common late stage symptom of Lyme disease.

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Targeting Cell Membrane Proteins to Combat Drug Resistance

Certain membrane proteins specialize in transporting molecules out of cells – a problem for the efficacy of cancer medication and antibiotics. Now a team has investigated the transport mechanism of a bacterial membrane protein using an artificially produced antibody fragment.
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Cartilage Ear 3D-printed Without Scaffolding

A new approach to bioprinting has been demonstrated in a study that successfully 3D-printed biological tissues without scaffolds using "ink" made up of only stem cells.
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Chemists’ Success in Synthesis Drives Development of Anti-cancer Agent

Researchers have now synthesized sufficient quantities of E7130, a drug candidate from the halichondrin class, to enable for the first time rigorous studies of its biological activity, pharmacological properties, and efficacy.
Shoulder Pain Relief for Wheelchair Users With Spinal Cord Injury content piece image
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Shoulder Pain Relief for Wheelchair Users With Spinal Cord Injury

Researchers report initial results for a minimally invasive intervention for relief of chronic refractory shoulder pain in upper-limb dependent individuals with spinal cord injury.
Discovery Could Help Treat People With Cardiovascular Disease content piece image
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Discovery Could Help Treat People With Cardiovascular Disease

Researchers have found a link between a peptide called apelin and a reduction of abdominal aortic aneurysms that was shown to dramatically reduce mortality in mice. They are using this knowledge to develop a new medical therapy to treat cardiovascular disease.
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