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Powerful Antibody Inhibits Multiple Strains of Norovirus
An antibody has been identified that broadly inhibits multiple strains of pandemic norovirus, a major step forward in the development of an effective vaccine for the dreaded stomach virus.
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Starving Cancer: Drug Drains Melanoma Cells of Their Energy
Researchers have found that two structurally similar compounds – deguelin and rotenone, naturally occurring pesticides produced by many plant species – interfered with melanoma cancer cells’ metabolism. Further testing with deguelin showed that it inhibited oxygen consumption in the cells’ mitochondria, effectively starving the cells of energy.
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Drug Boosts Bone Growth in Children With Dwarfism in Four-year Study
Researchers report that an experimental drug called vosoritide, allowed the average annual growth rate to increase in a study of 35 children and teenagers with a form of dwarfism. The average boost in height per year was ~6 centimeters (2.4 inches) which is close to growth rates among children of average stature.
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Bitcoin Has a Bigger Carbon Footprint Than Sri Lanka
Researchers have conducted the first analysis of Bitcoin power consumption based on empirical data. They found that the cryptocurrency's carbon emissions measure up to those of Kansas City--or a small nation. The study suggests that cryptocurrencies contribute to global carbon emissions, an issue that must be considered in climate change mitigation efforts.
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Algorithm Tells Robots Where Humans Are Headed
Improvements to a prediction algorithm used in a car manufacturing plant could help robots and humans work better together when sharing the same floor space, whilst maintaining efficiency.
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Cellular Component That Contributes to Lyme Arthritis Uncovered
Biochemist Brandon Jutras has discovered the cellular component that contributes to Lyme arthritis, a debilitating and extremely painful condition – the most common late stage symptom of Lyme disease.
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Targeting Cell Membrane Proteins to Combat Drug Resistance
Certain membrane proteins specialize in transporting molecules out of cells – a problem for the efficacy of cancer medication and antibiotics. Now a team has investigated the transport mechanism of a bacterial membrane protein using an artificially produced antibody fragment.
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Cartilage Ear 3D-printed Without Scaffolding
A new approach to bioprinting has been demonstrated in a study that successfully 3D-printed biological tissues without scaffolds using "ink" made up of only stem cells.
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Chemists’ Success in Synthesis Drives Development of Anti-cancer Agent
Researchers have now synthesized sufficient quantities of E7130, a drug candidate from the halichondrin class, to enable for the first time rigorous studies of its biological activity, pharmacological properties, and efficacy.
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Shoulder Pain Relief for Wheelchair Users With Spinal Cord Injury
Researchers report initial results for a minimally invasive intervention for relief of chronic refractory shoulder pain in upper-limb dependent individuals with spinal cord injury.
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