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AI Tool Recognizes Amyloid Plaques in Brain Tissue Samples
Researchers at UC Davis and UC San Francisco have found a way to teach a computer to precisely detect one of the hallmarks of Alzheimer's disease in human brain tissue, delivering a proof of concept for a machine-learning approach to distinguishing critical markers of the disease.
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The Next Generation of Hearing Aids Could Utilize a Listener's Brainwaves
A new study suggests that the next generation of hearing aids might match a listener's brainwaves with the "soundprint" of a speaker's voice, using that information to automatically turn up the volume on that speaker.
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Progress in Priming Stem Cell Cardiomyocyte Maturation
Speeding up the transformation of induced pluripotent stem cells into cardiomyocytes is of interest for researchers involved in regenerative medicine, and drug development for cardiac diseases.
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A Bite Out of the Blood-brain Barrier
Molecules from the immune system of a jawless parasitic fish could help lead the way to more effective treatments for multiple brain ailments, including cancer, trauma and stroke.
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Smile for the Camera!
Scientists have developed a method with which an enzyme at work can be “photographed”, making it possible to better understand the function of important biomolecules.
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Chip Platform a Tool for Modeling Drug Effects on Unborn Children
ETH researchers have combined embryonic cells and liver cells in a new cell culture test. This combination lets them detect adverse effects that new medications may have on embryos early on in the drug development process.
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Conquering Cancer’s Infamous KRAS Mutation
Scientists from Sanford Burnham Prebys and PHusis Therapeutics have shown that a compound called PHT-7.3 shrinks KRAS-driven tumors in mice.
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New Library Improves Chemical Reaction Data
In of organic chemistry, reactions are notoriously difficult to analyze. As a result, reaction data in chemoinformatics has been much less developed than information about single molecules. In a new project, titled CGRtools, researchers solved a number of problems to better handle reaction information. The software library is significantly richer in functionality than all the existing tools.
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Blocking Cell Death a Therapeutic Approach for Rheumatoid Arthritis
The finding that a protein called A20 prevents macrophage death and protects against arthritis opens up new possibilities for the treatment of this debilitating disease.
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Alzheimer Therapy Proven Safe for Use in Humans in Phase I Trial
The Alzheimer drug candidate PRI-002 has successfully completed Phase I of clinical research involving healthy volunteers. When administered daily over a period of four weeks, the active substance proved to be safe for use in humans. The next milestone will be the proof of efficacy in patients in clinical Phase II.
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