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A new compound developed by University of Sheffield experts has been shown to kill antibiotic resistant gram-negative bacteria, including E. coli.

Leveraging artificial intelligence techniques, researchers have demonstrated that mutations in so-called 'junk' DNA can cause autism.

Researchers investigated the effect of e-liquids on endothelial cells that line the interior of blood vessels. When grown in a lab, endothelial cells exposed to the e-liquids – or to blood collected from e-cigarette users shortly after vaping – were shown to be less viable and exhibit significantly increased levels of molecules implicated in DNA damage and cell death.

Charcot-Leyden Crystals are made from the protein Galectin-10 and were discovered in the airways of asthmatics as early as 1853. However, the crystals have been largely ignored by scientists, and their actual link to disease remained unknown, until now.

While many regenerative medicine applications are being pursued, the ability to track cells after transplant and determine their therapeutic efficacy is a challenge. Could exosomes, circulating cell-derived vesicles, hold the key?

Mitochondria, the "batteries" that produce our energy, interact with the cell’s nucleus in subtle ways previously unseen in humans, according to research published today in the journal Science.

Scientists have developed a human model in which they use organoids, or mini organs, to study the function of specific genes that are mutated in liver cancer.

It may one day be possible to reverse abnormal embryonic brain development linked to Down syndrome (DS) and improve cognitive function by therapeutically targeting a key gene known as OLIG2 prenatally, suggests newly published findings.

A certain group of cancer drugs (MEK Inhibitors) activate the cancer-promoting Wnt signaling pathway in colorectal cancer cells. The findings suggest a possible explanation for why these drugs are not effective in colorectal cancer.

Researchers have achieved material magnetization switching on the shortest timescales, at a minimal energy cost, thus creating a prototype of energy-efficient data storage devices.