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Gene Linked to ALS Disrupts Neuron Structure and Function
A study has described how a gene mutation linked to amyotrophic lateral sclerosis (ALS) disrupts the stability of neurons and “chokes off” their nuclei, impairing their function, and suggests that an anti-cancer drug could improve stability in lab models.
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Using an Octopus Brain To Understand Memory
Researchers have uncovered the neural architecture governing the learning processes of the enigmatic Octopus vulgaris. The research presents a promising model for studying memory networks.
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Genetically Modified Neural Stem Cells Show Potential for Spinal Cord Injuries
A research team has recently made a significant advancement in spinal cord injury treatment by using genetically modified human neural stem cells.
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Some Costly Cancer Drugs Can Have Unclear Patient Benefits
New cancer drugs are being launched rapidly before their long-term effectiveness for patients can be evaluated. A new study suggests that there is still a lack of evidence for many new cancer drugs, even several years after their launch.
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Study Sheds Light on Understanding Drugs' Impact on the Body
Research reveals detailed maps of how drugs are transformed in the body, how their levels change over time and how these changes are directly related to the body's biochemical responses.
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How Does the Vaginal Microbiome Eat To Survive?
Researchers examined how vaginal bacteria access glycogen, which is thought to be their key source of nutrition.
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Researchers Design Programmable DNA Hydrogels for Advanced Cell Culture
Researchers have developed a dynamic DNA-crosslinked matrix by combining classical synthetic polymers with programmable DNA crosslinkers. DNA’s highly specific and predictable binding gives unparalleled control over key mechanical properties.
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Blood Cancer Therapy Granted Accelerated FDA Approval
The FDA has given the green light to Elrexfio™ (elranatamab-bcmm), granting it accelerated approval to treat adults with multiple myeloma – a type of blood cancer – who have received at least four previous rounds of certain therapies.
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Use of Metformin Investigated in Prostate Cancer Treatment
Mortality rates for metastatic prostate cancer remain high, but new research has identified the mechanism behind the cancer's spread and researched whether the diabetes drug, metformin, could help.
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Ion Channel "Switches" Control Dopamine Release in the Brain
Scientists from the University of Washington (UW) School of Medicine have identified two ion channel “switches” in mice that regulate the release of dopamine in the brain.
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