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Drug Developed to Overcome Ibrutinib Resistance in Mantle Cell Lymphoma content piece image
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Drug Developed to Overcome Ibrutinib Resistance in Mantle Cell Lymphoma

A study at The University of Texas MD Anderson Cancer Center demonstrated how a small molecule drug discovered at the institution may help overcome resistance to treatment with ibrutinib in patients with mantle cell lymphoma.
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Revealing the Medicinal Potential of Honey Through Its Proteins

Honey is a culinary staple that can be found in kitchens around the world. Humans have used honey throughout history, and its long shelf life and medicinal properties make it a unique, multipurpose natural product. Now, researchers report new data on honey proteins that could lead to new medicinal applications.
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Targeting Ribosome Biogenesis as a Novel Approach for Multi-Stage Cancer Treatment

Nearly ninety per cent of all cancer patient deaths are due to metastasis. A study shows that a process that allows the cells to metastasise is aided by the synthesis of new ribosomes, the cell components in which proteins are produced.
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Broccoli Compound May Restore Brain Chemistry Imbalance Linked to Schizophrenia

Researchers say they have further characterized a set of chemical imbalances in the brains of people with schizophrenia related to the chemical glutamate. And they figured out how to tweak the level using a compound derived from broccoli sprouts.
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Pilot Study Finds Cherries a Sweet Solution for Lowering Blood Pressure

Montmorency tart cherries reduced systolic blood pressure, insulin levels and insulin concentrations in adults with metabolic syndrome participating in a small pilot study.
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Bacteria’s Secret Signaling System Opens Doors for Antibiotic Therapy

Researchers have discovered a previously unknown signaling pathway that regulates surface proteins on bacteria that can lead to new targets for antibiotics.
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Cancer Research UK and Aptamer Therapeutics Announce Drug Development Partnership

Aptamer Therapeutics Limited is pleased to announce a new collaboration with Dan Wiseman and the Oglesby Leukaemia Research Programme at the University of Manchester and Cancer Research UK. The project will explore the potential of aptamers as therapeutic agents for the treatment of chronic myelomonocytic leukemia and other myeloid malignancies.
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Genetic Diversity of Tumors a Driver of Differential Immunotherapy Response

Experimental and clinical evidence presents new reasons why about half of patients whose tumors are marked by a large number of mutations from "mismatch repair genetic deficiency" fail to respond to immunotherapy.
Eye’s Vulnerability to Macular Degeneration Revealed content piece image
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Eye’s Vulnerability to Macular Degeneration Revealed

Scientists have found significant differences in the shape and biology of the same type of cell taken from different parts of the retina. The results could help explain why the macular region of the eye is more susceptible to disease than the peripheral retina and reveals a protective mechanism that may be disrupted in disease.
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“Smart Cells” Improve Pharmaceutical Raw Material Production

Researchers have developed an integrated synthetic biology system to construct new metabolic pathways and enzymes within microbes. By incorporating a "Design, Build, Test, Learn" (DBTL) workflow, the production of pharmaceutical raw materials could be systematically optimized.
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