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Mapping Route to Recurrence in Breast Cancer Cells
Residual, treatment-resistant tumor cells aren't like the original cancer cells. Instead, they lay low and switch on a horde of small signaling proteins. Understanding their behavior could lead to the discovery of druggable targets.
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The Key to Targeting Dormant Cancer Cells
Researchers have identified what keeps some cancer cells dormant – a finding which could uncover new approaches to preventing the spread of cancer.
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Injectable Tissues Closer to Reality With Cell-encapsulating Device
A simple injection that can help regrow damaged tissue has long been the dream of physicians and patients alike. A new study takes a big step towards making that dream a reality with a device that makes encapsulating cells much faster, cheaper and more effective.
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Colorectal Cancer Vaccine Proves Safe in Phase I Trial
A new colorectal cancer vaccine showed positive results in the phase 1 clinical trial to demonstrate that the approach is safe. The patients treated had no signs of serious adverse events and samples of their blood contained markers of immune activation – an early indication that the vaccine could activate immune cells to fight colorectal tumors and metastases.
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Personalized Cancer Therapy Trial Shows Encouraging Results
A newly published study has demonstrated the potential of using transcriptomics to help get cancer patients on treatments they're most likely to benefit from.
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Meal Timing Can Make or Break Your Cells' Circadian Rhythm
It is well known that exposure to daylight keeps our body clock in check. But what impact does meal timing have? A new study published in Cell helps answer this question and provides new insights on how cells keep a circadian rhythm. The study also has important implications for shift workers and travelers wanting to avoid jet lag.
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Drugs to Prevent Stroke and Dementia Show Promise in Early Trial
Treatments that prevent recurrence of types of stroke and dementia caused by damage to small blood vessels in the brain have moved a step closer, following a small study.
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How a Shrub May Enable the “Impossible” in Treating Addiction
Scientists used a compound found in a shrub native to Africa to reveal the three major shapes of the serotonin transporter, a protein in the brain linked to anxiety and depression.
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Novel Synthesis Strategy Speeds Up Identification of Simpler Versions of Natural Product
A new chemical synthesis strategy to harvest the rich information found in natural products has led to the identification of novel, simpler derivatives with potential to selectively protect neurons, important for neurodegenerative diseases like Alzheimer’s disease, or to prevent the body’s immune system from rejecting organ transplants, according to a Baylor University-led study.
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Scientists Crack the Chemical Code of Complex “Anti-tumor Antibiotic”
After 20 years of dedicated research, scientists have cracked the chemical code of an incredibly complex "anti-tumor antibiotic" known to be highly effective against cancer cells as well as drug-resistant bacteria, and have reproduced it synthetically in the lab for the first time.
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