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Tissue from a mouse tongue as seen under a microscope with localization of the ORAI1 protein in the tissue.
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"Gates of Heaven" Calcium Channel Could Provide Therapy Target for Oral Cancers

The ORAI1 calcium channel – named after figures from Greek mythology – fuels the growth of oral cancers and pain, but could provide a new approach to treating oral cancer.
Two boys playing in a garden.
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Novel Tool for Diagnosing Autism in Children

Three clinical studies of more than 1,500 children tested whether objective measurements can help diagnose children with autism before the age of three years.
White circular pills on a blue background.
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Multiple Sclerosis Drug May Also Be Effective Against Alzheimer's

A team of researchers at the University of Kentucky has found that a drug used to treat multiple sclerosis (MS) is potentially effective as a therapy for Alzheimer’s disease.
HIV attacking a human cell.
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New HIV Drug Tackles Multi-Drug Resistance

Through collective pursuit in the research world, a new class of HIV treatment was born: long-acting HIV medications that target the capsid of HIV-1, which is a conical structure that harbors its genome.
A human brain on a holographic blue and purple background.
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How Immunotherapies Clear the Brain of Alzheimer's Proteins

Studies have shown that lecanemab slows cognitive and functional decline in early-stage Alzheimer’s patients. But as with many other cutting-edge therapies, we know more about lecanemab’s effectiveness than we do about how it actually works.
Someone pouring pills out into their hand from an orange pill bottle.
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Statins May Lower Cancer Risk for Ulcerative Colitis Patients

Cholesterol-lowering statins might protect patients with ulcerative colitis from developing and dying from colorectal cancer. Statin treatment was also associated with a lower risk of death regardless of cause in patients with ulcerative colitis.
Illustration of a tumor.
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Brain Tumor Gene Therapy Shows Early Promise in First-in-Human Trial

Combination drug and immunotherapy treatment can extend survival in patients with gliomas, a highly aggressive form of brain cancer, suggests a new Phase 1, first-in-human trial.
A psychedelic brain.
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Single Psilocybin Dose Once Again Found To Relieve Major Depression

A new clinical trial has reaffirmed the potential of the magic mushroom-derived compound psilocybin to relieve the symptoms of major depression. The study, published in the Journal of the American Medical Association, is the latest to suggest that psychedelic drugs can provide a new treatment option in psychiatry.
Computer-generated image of cancer cells.
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Cancer Drug “Envelope” Protects Against Heart-Damaging Side Effects

Researchers have developed a protein “envelope” that surrounds the cancer drug doxorubicin, both increasing its chances of being taken up by cancer cells and decreasing its toxic effects on lab-grown heart cells.
Double helix structure of DNA.
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Largest Genetic Study of Epilepsy to Date Uncovers Why Epilepsy Develops

The largest genetic study of its kind has discovered changes in our DNA that increase the risk of developing epilepsy. The research advances our knowledge of why epilepsy develops and may inform the development of new treatments for the condition.
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