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A Personalized Microfluidic Model for Kidney Cancer Drug Screening
One way to treat the most common type of kidney cancer is to use anti-angiogenic drugs to cut off the blood supply to the tumors, but patients respond differently to the drugs, and choosing the wrong one can make the cancer grow faster.
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Backtracking for Accurate Gene Transcription
Scientists from the Hong Kong University of Science and Technology (HKUST) have recently uncovered the mechanisms of how RNA polymerase II performs intrinsic cleavage reaction to proofread RNA transcriptions, shedding light on how mis-regulation of accurate transcription can lead to diseases including cancer and Alzheimer’s disease.
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Building With DNA “Lego”
Scientists have created a three-dimensional cage from both protein and DNA building blocks through the use of covalent protein-DNA conjugates.
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Cell Therapy Delays Disease Progression in ALS Mice
A new University of South Florida preclinical study finds that the regenerative cell therapy boosts motor neuron survival by repairing the blood-spinal cord barrier.
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New Mouse Model Replicates Rare Neurological Disease
A new mouse model for the rare neurological disorder Joubert Syndrome has been developed by scientists who hope it will accelerate research to understand how the disease develops as well as help develop and evaluate therapeutic approaches.
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Gold-enhanced Biochip Detects Markers at Minute Concentrations
The difficulty in spotting minute amounts of disease circulating in the bloodstream has proven a stumbling block in the detection and treatment of cancers that advance stealthily with few symptoms. With a novel electrochemical biosensing device that identifies the tiniest signals these biomarkers emit, NJIT researchers are hoping to bridge this gap.
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Computer-created Bacterial Genome is World First
Scientists have developed a new method that greatly simplifies the production of large DNA molecules containing many hundreds of genes. With this method, they have built the first genome of a bacterium entirely designed by a computer algorithm. The method has the potential to revolutionise biotechnology.
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Maybe "Leaky Gut" Should Be Considered in HIV Treatment
HIV-positive people treated with antiretroviral therapy who had high levels of autoantibodies also had increased levels of Staphylococcus aureus products in their blood, raising new possibilities of a "leaky gut" mechanism in HIV pathology.
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"Wearable" Device Captures Cancer Cells From Blood
By capturing more cancer cells than blood draw screening, this device could help doctors understand a tumor’s biology and make decisions about treatment.
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Addiction Vaccine Research Awarded Funding
Victoria University of Wellington scientists developing ground-breaking new vaccines to treat drug addiction have received one of fifteen $150,000 Explorer Grants from the Health Research Council of New Zealand.
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