Inhibiting Key Enzyme Selectively Kills Melanoma Cells, Study Shows
Researchers have shown that inhibiting a metabolic enzyme, called glutaryl-CoA dehydrogenase, selectively kills melanoma cells and stops tumor growth.
Cancer Cells That Survive After Treatment Lead to Relapse
Cancer recurrence can be due to a population of drug-resistant "persister" cells surviving chemotherapy. Researchers have now identified how these persister cells form.
Drug Combination Halts Tumor Growth and Resistance in Mice
An experimental combination of two drugs in mouse models halts the progression of small cell lung cancer, findings that may lead to better treatments for the deadliest form of lung cancer.
Tree Compound Has Potential To Kill Drug-Resistant Bacteria
New research has found that hydroquinine, a compound found in the bark of trees and used as an anti-malarial, also has bacterial killing activity.
Anticancer Drug Produced by Reprogrammed Yeast
Researchers have used genetically engineered yeast to synthesize a chemotherapeutic drug that is susceptible to supply shortages.
Repurposed Old Drugs May Offer Hope Against Chronic Pain
A newly identified link between chronic pain and lung cancer in mice offers hope for the management of chronic pain, and demonstrates that repurposing old drugs such as fluphenazine may be effective for nerve pain.
Adjuvant Derived From Marine Sponges Boosts Effect of COVID-19 Vaccine
In a new study, researchers report a substance that boosted the immune response to an experimental COVID-19 shot in mice by 25 times, compared to injection with the vaccine alone.
New Preclinical Mouse Model May Accelerate Thymus Gland Cancer Research
A new preclinical model for thymic cancer has revealed insights into how a common mutation found in thymic epithelial tumors sparks their formation.
Short Blast of Anti-Aging Drug Proves Effective in Animal Study
Research in laboratory animals has shown that brief exposure to rapamycin has the same positive effects as lifelong treatment, opening new doors for a potential application in humans.
Breakthrough in Developing an Oral Insulin Tablet
Researchers have discovered that insulin from the latest version of their oral tablets is absorbed by rats in the same way that injected insulin is.