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The ferret has been established as a suitable model for studying how to stop this tick-borne fever-inducing virus.

Following beta cell loss in mice, 1-2% of glucagon-producing α-cells spontaneously engage in insulin production. In this study, this was increased to 5%, providing new insights on cell flexibility and opening up therapeutic approaches for diabetes and other diseases caused by cell death.

Researchers have developed a new method of analysis that maps the location of proteins in the cell. The information has been compiled in a database that is accessible to researchers around the world. The method of analysis, which has been published in the journal Molecular Cell, can also provide in-depth knowledge of disrupted cell function in cancer and other diseases.

MIT researchers have now designed an inhalable form of mRNA. This aerosol could be administered directly to the lungs to help treat diseases such as cystic fibrosis, the researchers say.

A compound derived from an ornamental plant in the primrose family is a leading candidate for the treatment of uveal melanoma, the most common eye cancer in adults.

With more than 1.8 million children in the U.S. being treated annually with drugs for attention deficit hyperactivity disorder (ADHD), the possibility that such drugs could damage their hearts has been a significant cause of concern for parents and physicians alike. Now, the results of a long-term study could allay many of those concerns.

A growing body of evidence supports the effectiveness of botulinum toxin injections in reducing the frequency of chronic migraine headaches.

By simultaneously tackling two mechanisms for cancer's growth, an experimental therapy reduced the spread of triple-negative breast cancer in a study conducted in mice.

Helping people with addictions has become a research passion for Purdue University researchers who is leading a team to make drug discoveries to support millions around the world dealing with alcohol use disorders, chronic pain and mood disorders. The team's recent discovery provides a new avenue for the development of medications that provide therapeutic relief for a patient without causing unwanted side effects.

Researchers describe a method allowing for the automation of DNA origami construction, vastly accelerating and simplifying the process of crafting desired forms, and opening the world of DNA architecture to a broader audience.