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Drug Improves Outcomes & Survival Rates in Patients with Bone Marrow Cancer
In the largest study of its kind, researchers at Newcastle University have led national research into the treatment of patients with newly diagnosed myeloma. The results, published by The Lancet Oncology, show an improvement for those who received ongoing therapy with a drug called lenalidomide, compared to those not receiving it.
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Precise Engineering of Graphene Could Benefit Lab-on-a-chip Applications
A team of NYU researchers has solved a longstanding puzzle of how to build ultra-sensitive, ultra-small electrochemical sensors with homogenous and predictable properties by discovering how to engineer graphene structure on an atomic level.
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Drug Seeks Out Receptors in Sarcoma Cells, Shrinks Tumors
A new compound that targets a receptor within sarcoma cancer cells shrank tumors and hampered their ability to spread in mice and pigs, a study from researchers at the University of Illinois reports.
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Defective Metabolic Pathway Corrected in Aged Mouse T Cells
T cell-mediated immune responses are compromised in aged individuals, leading to increased morbidity and reduced response to vaccination. Finding new ways to boost T cell immunity in the elderly is key for enhancing their immune competence.
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Ebola-fighting Protein Discovered
A human protein called RBBP6 helps fight the Ebola virus by interfering with its replication cycle, and a small molecule drug that mimics the function of this protein could one day be an effective therapy against the deadly disease, according to a new study.
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Loss of Tight Junction Protein Promotes Development of Precancerous Cells
Tight junctions are multi-protein complexes that serve as barriers in epithelial tissues such as the skin or lining of the gut. Loss of a specific tight junction barrier protein, claudin 18, occurs in the majority of gastric cancer patients and is correlated with poor prognosis in patients with advanced gastric cancer.
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Deep-Learning Technique Reveals “Invisible” Objects in the Dark
Small imperfections in a wine glass or tiny creases in a contact lens can be tricky to make out, even in good light. In almost total darkness, images of such transparent features or objects are nearly impossible to decipher. But now, engineers at MIT have developed a technique that can reveal these “invisible” objects, in the dark.
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Fighting Obesity: Unearthing the Fat-Fighting Power of Clays
Investigating how clay materials can improve drug delivery, UniSA researcher and PhD candidate, Tahnee Dening serendipitously discovered that the clay materials she was using had a unique ability to "soak up" fat droplets in the gut.
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Watch Small-molecule Drug Interactions Inside Cells
Now, researchers reporting in ACS’ journal Analytical Chemistry have developed a method to visualize whether drugs are regulating protein–protein interactions inside cells.
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A New Formulation Helps the Medicine Go Down
Scientists have developed a novel pharmaceutical formulation to administer triclabendazole - an anti-parasitic drug used to treat a type of flatworm infection - in billions of tiny capsules.
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