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Drug Candidate Could Recover Vocal Abilities Lost to ADNP Syndrome
A new Tel Aviv University study finds that the drug candidate CP201, also known as NAP, may improve vocal communication abilities that are underdeveloped in Activity-dependent neuroprotective protein (ADNP) patients.
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New Inflammation Inhibitor Discovered
A multidisciplinary team of researchers led from Karolinska Institutet in Sweden have developed an anti-inflammatory drug molecule with a new mechanism of action.
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Leukemia Stem Cells Rely on Amino Acids for Survival
Clinically relevant eradication of leukemia stem cells could be achieved with drugs that target their metabolic vulnerabilities.
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Scorpion Venom Can Shuttle Drugs into the Brain
Researchers at IRB Barcelona modify chlorotoxin—a small protein present in scorpion venom with blood-brain barrier permeability—to transport drugs into the brain.
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Molecular Mechanisms of Ancient Herbal Remedies
Analysis of leaf extract reveals novel chemistry for therapeutic ion channel activation.
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Ketone Shuttle Coordinates Response to Liver Fibrosis
A metabolite shuttle, or dialogue, provides a connection between hepatocyte and macrophage cell types in the liver and helps protect against tissue fibrosis.
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Anti-Malaria Drugs Show Promise in Treating Cancer – Now We Know Why
Anti-malaria drugs known as chloroquines have been repurposed to treat cancer for decades, but until now no one knew exactly what the chloroquines were targeting when they attack a tumor. Now, researchers say they have identified that target - an enzyme called PPT1 - opening up a new pathway for potential cancer treatments.
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Dramatic Increase in E-Cigarette Use Among Youth
Sharp rise in e-cigarette use results in uptick in overall tobacco product use; prompts new, forceful steps by FDA to firmly confront and reverse youth epidemic.
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Rainforest Vine Compound Starves Pancreatic Cancer Cells
Researchers have identified a compound from a Congolese plant that has strong "antiausterity" potential, making pancreatic cancer cells susceptible to nutrient starvation.
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Non-circulating T Cells Vital for Protection against Salmonella
Noncirculating T cells are relatively unknown, but appear to be a vital component of immunity to Salmonella infection — and should be the focus of vaccine strategies.
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