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Pancreatic Cancer: Mechanism of treatment-resistance discovered
Despite decades of research, treatments that can target a common mutation in the most frequently diagnosed type of pancreatic cancer have remained elusive. Now, researchers report they have discovered a mechanism of resistance to a treatment they’d identified as promising.
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HPV-Positive Throat Cancer Patients Should Keep Taking Chemotherapy
Patients with human papillomavirus (HPV)-positive throat cancer should carry on receiving chemotherapy rather than switching to a targeted cancer drug during curative radiotherapy, new clinical trial results have shown.
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Peanut Allergy Treatment Ready for FDA Review
Study shows it is possible for some people with peanut allergy to protect themselves from accidental ingestion by building up their tolerance to peanut over time.
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Membrane Proteins Ejected Directly from Cell Membrane to Mass Spec
A new approach to analyzing cell membrane proteins in situ could revolutionize the way in which we study diseases, such as cancer, metabolic and heart diseases.
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Arming Drug Hunters: Chemists design new reaction for drug discovery
The pair of Colorado State University organic chemists have forged a powerful new tool for drug hunters - a simple, elegantly designed chemical reaction that could fling open an underexplored wing of biologically relevant chemistry.
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Drug Candidate Could Recover Vocal Abilities Lost to ADNP Syndrome
A new Tel Aviv University study finds that the drug candidate CP201, also known as NAP, may improve vocal communication abilities that are underdeveloped in Activity-dependent neuroprotective protein (ADNP) patients.
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New Inflammation Inhibitor Discovered
A multidisciplinary team of researchers led from Karolinska Institutet in Sweden have developed an anti-inflammatory drug molecule with a new mechanism of action.
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Leukemia Stem Cells Rely on Amino Acids for Survival
Clinically relevant eradication of leukemia stem cells could be achieved with drugs that target their metabolic vulnerabilities.
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Scorpion Venom Can Shuttle Drugs into the Brain
Researchers at IRB Barcelona modify chlorotoxin—a small protein present in scorpion venom with blood-brain barrier permeability—to transport drugs into the brain.
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Molecular Mechanisms of Ancient Herbal Remedies
Analysis of leaf extract reveals novel chemistry for therapeutic ion channel activation.
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