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Chemical diagram showing cyclopropanes in drugs used to treat COVID-19, asthma, hepatitis C and HIV/AIDs.
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Simple Chemical Process Creates Drug Potency-Increasing Structures

Researchers have identified and demonstrated a safe, efficient and practical way to create cyclopropanes using a previously undescribed chemical process.
White pills on a blue background.
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New Drug Formulation Could Improve HIV Treatment for Children

Researchers helped evaluate a new drug formulation for children with HIV.
The molecular structure of a protein, shown as purple folds and helixes.
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Deep Learning Improves Protein Design

A research team has used deep learning methods to support de novo protein design, resulting in a 10-fold increase in success rates for a protein binding with its target.
The colon wall with sensory neurons labeled with fluorescent dyes.
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Five Subtypes of Colon Sensory Colon Neurons Identified

Scientists define five types of colon neurons specialized for sending different signals to the brain.
Three lines of white power with a credit card and a rolled up £20 note.
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Cravings and Rewarding Effects of Cocaine Impacted by Gut Microbiome

A new study has shown that changes to the gut microbiome have significant effects on cocaine use and cravings after withdrawal.
A blue light orb.
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Enzymes That Can Be Controlled With Blue Light

Researchers have gained new insights into the functioning of a protein found in bacteria, whose enzymatic activity is activated by blue light.
Four types of medicinal tablets.
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Drug Screening Helps Identify Effective Therapeutic Strategies for Pediatric Cancer

In a landmark study of 125 Australian children with high-risk cancer, researchers have found that they can improve the chances of finding the right drug to kill their individual cancer through a new system of rapid drug screening.
Two pairs of hands each holding a pen.
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Consent Document Translation Costs Could Impact Inclusivity of Clinical Trials

According to a study, cancer research centers conducting clinical trials could enroll more patients from underrepresented racial and ethnic groups by placing greater emphasis on relieving investigators of the costs of translating consent documents.
A plaster on the upper arm of a person wearing a white t-shirt.
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Three Doses of COVID Vaccine Effective in Vulnerable Populations

In a study, vulnerable people at risk of severe COVID-19 achieved good antibody levels after three doses of mRNA vaccine.
A viral protein.
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Novel Antiviral Works by Bursting Their Bubble-Like Membranes

Targeting the membrane of a virus, rather than its proteins, could lead to a new generation of antivirals.
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