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Simple Chemical Process Creates Drug Potency-Increasing Structures
Researchers have identified and demonstrated a safe, efficient and practical way to create cyclopropanes using a previously undescribed chemical process.
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New Drug Formulation Could Improve HIV Treatment for Children
Researchers helped evaluate a new drug formulation for children with HIV.
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Deep Learning Improves Protein Design
A research team has used deep learning methods to support de novo protein design, resulting in a 10-fold increase in success rates for a protein binding with its target.
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Five Subtypes of Colon Sensory Colon Neurons Identified
Scientists define five types of colon neurons specialized for sending different signals to the brain.
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Cravings and Rewarding Effects of Cocaine Impacted by Gut Microbiome
A new study has shown that changes to the gut microbiome have significant effects on cocaine use and cravings after withdrawal.
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Enzymes That Can Be Controlled With Blue Light
Researchers have gained new insights into the functioning of a protein found in bacteria, whose enzymatic activity is activated by blue light.
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Drug Screening Helps Identify Effective Therapeutic Strategies for Pediatric Cancer
In a landmark study of 125 Australian children with high-risk cancer, researchers have found that they can improve the chances of finding the right drug to kill their individual cancer through a new system of rapid drug screening.
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Consent Document Translation Costs Could Impact Inclusivity of Clinical Trials
According to a study, cancer research centers conducting clinical trials could enroll more patients from underrepresented racial and ethnic groups by placing greater emphasis on relieving investigators of the costs of translating consent documents.
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Three Doses of COVID Vaccine Effective in Vulnerable Populations
In a study, vulnerable people at risk of severe COVID-19 achieved good antibody levels after three doses of mRNA vaccine.
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Novel Antiviral Works by Bursting Their Bubble-Like Membranes
Targeting the membrane of a virus, rather than its proteins, could lead to a new generation of antivirals.
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