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Scientists Infected People With Hookworms To Improve Their Metabolic Health
A world-first human trial has revealed that inoculation with live hookworms resulted in modest improvements in insulin resistance in a small study of 40 participants at risk for type 2 diabetes.
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New Method Helps To Advise on Medication Use While Breastfeeding
Researchers have developed a novel metric for an underserved research area to aid healthcare providers in advising on maternal medication use for breastfeeding mothers or nursing persons.
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Genomics Information Is Critical for Battling Pathogens
Genomic sequencing had a huge impact in the global response to COVID-19, and the technology improved as more researchers put it to use.
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Thousands of Cancer Patients Could Benefit From Existing Drugs
PARP inhibitor drugs are currently used to treat some breast, ovarian and prostate cancers. New research suggests these drugs could also be used to treat cancers with changes to the SF3B1 gene.
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10 Blood Proteins Associated With Mortality in Severe Burns
Researchers have used mass spectrometry to identify ten blood proteins associated with mortality in severe burns. Three of these proteins may serve as targets for developing new treatment methods for burns.
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CAR-T Cell Therapy Attacks Late-Stage Ovarian Cancer With a Single Dose
CAR-T immune therapies could be effective against solid tumors if the right targets are identified, a new study led by University of Illinois Urbana-Champaign researchers suggests.
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Cancer Drug Selectively Kills Tumor Cells in Preclinical Study
In a preclinical study, researchers have shown how a new cancer drug was able to kill cells from all tested solid tumors while leaving healthy cells unaffected. The drug, which targets a protein previously thought “undruggable”, is now being tested in a Phase 1 clinical trial.
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Mouse Study Raises Possibility of ALS Immunotherapy Treatment
Researchers have modulated a protein related to the immune system to slow the progress of amyotrophic lateral sclerosis (ALS) in mice.
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New Tactic To Beat Bacterial Resistance Discovered
Scientists found a new class of molecules that inhibit the efflux pump and make the antibiotic effective again.
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Tiny Amounts of Hydrogen Sulfide Improves Health and Aging in Worms
Future therapies to help people live healthy lives for longer could be developed from drugs that release tiny amounts of the gas hydrogen sulfide, new research in C. elegans has indicated.
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