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Bioengineered lungs have been successfully transplanted into adult pigs, with remarkable results.

"This new class of compounds stop cancer cells dividing and proliferating by switching off their ability to continue the cell cycle,” says joint research leader Associate Professor Anne Voss of the Walter and Eliza Hall Institute of Medical Research and the University of Melbourne. “The technical term is cell senescence, but essentially the cells are put to sleep."

A new drug-delivery technology which uses red blood cells (RBCs) to shuttle nano-scale drug carriers, called RBC-hitchhiking (RH), has been found in animal models to dramatically increase the concentration of drugs ferried precisely to selected organs, according to a study published in Nature Communications.

Studies of preterm delivery are logistically difficult, but this organ-on-a-chip is bound to help.

More than 60 years after the drug thalidomide caused birth defects in thousands of children whose mothers took the drug while pregnant, scientists have solved a mystery that has lingered ever since the dangers of the drug first became apparent: how did the drug produce such severe fetal harm?

Researchers have discovered that certain drug cocktails help targeted therapies attack cancer more efficiently while lessening common side effects, according to a new study.

Scientists have discovered a new protein, called iTAP, that controls the levels of TNF in circulation by regulating its release from immune cells. These findings open avenues for the design of improved therapeutics for inflammatory diseases.

NISTmAb, the world's first standardized monoclonal antibody has become a valuable tool for biomanufacturers developing new biologic therapies for cancers, autoimmune disorders and infectious diseases.

A computational study has demonstrated that cancer cells proliferate less and in a less robust manner when their internal pH is lowered, that is to say it becomes more acidic.

Researchers have discovered a mechanism that causes the body to sabotage its own defenses against infection by visceral leishmaniasis, a fatal tropical disease. This discovery could help in the fight against a number of chronic infections.