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Sex Differences Revealed: Heart Failure Death Rates
Death from heart failure in men and women compared in a study of over 90 000 patients
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Fetal Gene Therapy Prevents Lethal Neurodegenerative Disease
Researchers have successfully prevented the development of a fatal neurodegenerative disorder, Gaucher disease, using fetal gene therapy, in mice. The study highlights the potential of using this approach to combat lethal neurodegenerative diseases affecting newborns.
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Some Like it Hot - Including Tree Shrews!
Spicy foods elicit a pungent or hot and painful sensation that repels most mammals. However, the tree shrew, a species closely related to primates, seems to violate this rule of thumb.
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Finding the Proteins That Unpack DNA
A new method allows researchers to systematically identify specialized proteins that unpack DNA inside the nucleus of a cell, making the usually dense DNA more accessible for gene expression and other functions.
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Nano and Micro Join Forces to Treat Osteoarthritis
There is currently no treatment for curing osteoarthritis, which affects 80% of the population over 75 years of age. But researchers who have been studying the problem have come up with a new treatment that delivers previously-identified active principles directly into the joint in the form of nanocrystals inserted into microparticles.
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Machine Learning Helps Predict Schizophrenia Treatment Outcomes
New research that used a machine-learning algorithm to investigate MRI images of schizophrenia patients has successfully identified response to antipsychotic treatment in 4 out of 5 patients.
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Key Role for Enzyme in Chagas Disease Response
Researchers describe the central role played by an enzyme called phosphatidylinositol 3-kinase gamma (PI3Kγ) in regulating the immune response against Trypanosoma cruzi, the protozoan parasite that causes Chagas disease.
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Fragile X: Drug Strategy Could Alleviate Behavioral & Cellular Deficiencies
Research in mice shows that a pharmacological strategy can alleviate multiple behavioral and cellular deficiencies in a mouse model of fragile X syndrome (FXS), the most common inherited form of intellectual disability and a major single-gene cause of autism spectrum disorders.
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Mouse Study Suggests That Dietary Fat, Not Carbs, Drives Obesity
A mouse study that made over 100,000 measurements of body weight and fat has concluded that the sole driver of obesity in mice is increased dietary fat content.
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Testosterone Effective at Combating Cachexia in Cancer Patients
Many cancer patients suffer from a loss of body mass known as cachexia. A new study shows that the hormone testosterone is effective at combatting cachexia in cancer patients and improving quality of life.
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