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Targeting the Engine Room of the Cancer Cell

Researchers at Columbia University Irving Medical Center (CUIMC) have developed a highly innovative computational framework that can support personalized cancer treatment by matching individual tumors with the drugs or drug combinations that are most likely to kill them.
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Integrated Lead Discovery: An Evolving Toolbox

A new SLAS Discovery review article offers an informative guide to the established and emerging tools available for early drug discovery and screening, and provides illustrative scenarios demonstrating considerations that drive decisions on choice of lead discovery tactics.
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Making Fragrant Fumes

Waste oil from orange, tea tree and eucalyptus essential oil production mixed with diesel provides a sweet-smelling biofuel blend with comparable performance to diesel-only fuel.
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Disease-Fighting 'Warheads' Hidden in Bacteria

Bacteria found in soil may harbor a potential game-changer for drug design. A new study by Scripps Research, published today in Nature Communications, suggests scientists could build better drugs by learning from bacteria-derived molecules called thiocarboxylic acids.
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Exploring Challenges in the Synthesis of Pharmaceutical Drugs

This summer, Wendell and Loretta Hess Professor of Chemistry Ram Mohan will travel to India and Hong Kong to deliver a series of post-graduate workshops on advanced concepts in organic synthesis.

His workshop “Advanced Concepts in the Synthesis of Pharmaceutical Drugs” at the Indian Institute of Technology Indore will explore the unique, real-world challenges in the pharmaceutical industry to synthesize drugs that are both commercially viable and eco-friendly.
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Modern Alchemists are Making Chemistry Greener

Ancient alchemists tried to turn lead and other common metals into gold and platinum. Modern chemists in Paul Chirik’s lab at Princeton are transforming reactions that have depended on environmentally unfriendly precious metals, finding cheaper and greener alternatives to replace platinum, rhodium and other precious metals in drug production and other reactions.
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Novel Method for Testing Vaccine Safety

Scientists from the Institut Pasteur, the CNRS and Sanofi Pasteur have recently developed a novel alternative method to animal testing that can be used to verify the safety of vaccines such as the yellow fever vaccine.
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Biometric System Measures Brainwaves, Creates Brain Password

The “brain password” could have implications in banking, law enforcement, airport security and other areas.
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Cryo-EM Reveals Interaction Between Major Drug Targets

For the first time, scientists have visualized the interaction between two critical components of the body's vast cellular communication network, a discovery that could lead to more effective medications with fewer side effects for conditions ranging from migraine to cancer.
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The Friedrich Schiller University Jena Partners with ACD/Labs to Advance its Analytical Data Management Strategy

Implementation of ACD/Spectrus as an analytical data management system helps researchers and students streamline NMR and MS data processing, interpretation, collaboration, and training.
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