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Protein Target Identified That Could Prevent Strokes
Scientists have identified a protein, called GPR68, that senses blood flow and tells small blood vessels called arterioles when to dilate. The researchers believe medications that activate GPR68 could one day be useful to treat medical conditions, including ischemic stroke.
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How Environmental Pollutants and Genetics Work Together in Rheumatoid Arthritis
It is well known that individuals with a particular version of human leukocyte antigen have an increased risk for rheumatoid arthritis, but there has been growing interest in the role of environmental pollutants. In a new mouse study, researchers probed the relationship between the two.
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Neuropeptide Y Y1 Receptor Structure Solved, Offers New Opportunities for Anti-obesity Drug Discovery
Scientists solve the crystal structure of Neuropeptide Y Y1 Receptor, offering new opportunities for anti-obesity drug discovery.
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Crystal Structure of Neuropeptide 1 Receptor Solved, Providing Therapeutic Angle For Obesity Treatment
An international team has uncovered the potential to beat obesity at the cellular level, characterizing for the first time a complex, little-understood receptor type that, when activated, shuts off hunger.
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Understanding Inflammation From the Inside Out
Researchers have developed a method that enables them to genetically modify immune cells, multiply them and visualize them in living organisms. The technique will better evaluate and study the the inflammatory process.
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Grafted Brain Organoids Provide Insight into Neurological Disorders
Salk scientists improve the growth of three-dimensional brain models to better understand autism, dementia, schizophrenia.
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Deceased Data: Should Your Online Remains Be Treated Like Physical Remains?
In 2018, your death doesn't just leave behind a body. It leaves behind a huge online footprint - your digital remains. A new study asks whether these remains should be treated and respected as a corpse would, and whether museums may provide a blueprint for the preservation process.
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Detecting Heart Disease with an AI App
The process of assessing and monitoring heart disease, the leading cause of death in the US, is often expensive and time-consuming. A new app that incorporates pulse data to diagnose arterial changes could simplify the whole process.
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Deficiency of Innate Immune Adaptor TRIF Linked to Neurodegeneration
Research has revealed that deficiency of the innate immune adaptor TRIF, which is essential for certain Toll-like receptor signaling cascades, significantly shortened survival time of ALS mice.
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Gastric Proton Pump Structure Determined
Researchers have for the first time determined the crystal structure of the gastric proton pump responsible for gastric acid secretion.
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