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HEx Technology Cracks Cryptic Codes Identifying Potential Therapeutic Compounds
Researchers have developed a technology, known as ‘HEx’, that can detect natural products from fungal species, products which are usually extremely difficult to identify. This approach could be used to find natural compounds with therapeutic potential – paving the way to novel antimicrobial drugs.
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Coordinated Data Alerts Help Lower Prescription Drug Risks
Opioids and benzodiazepines are the most common drug classes involved in overdoses. Now, a new electronic warning system has helped lower co-prescription of these drugs for high-risk patients.
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IONTAS and IGEM Therapeutics Collaborate to Identify Novel IgE Antibodies
The project will add to IGEM’s pipeline of drugs and expand upon IGEM-F, an IgE targeting ovarian and other cancers, currently in a Phase 1/2a study.
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Bacteria and Fungi Play Vital Roles in Social Insect Colonies
Researchers working on the Ribeirão Preto campus of the University of São Paulo (USP) in Brazil have discovered that a bacterium found in the microbiota associated with this leafcutter ant species produces the same pyrazines used by the ants to lay a trail to their nest. The main aim of the project is to explore the microbiota of Brazilian ants in search of natural molecules that can give rise to new drugs.
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Drug Combo Improves Survival of Women with Rare Uterine Cancer
Adding the monoclonal antibody drug trastuzumab - already used to treat certain breast cancers - to the chemotherapy regimen of women with a rare form of uterine cancer lengthens the amount of time their tumors are kept from growing, according to Johns Hopkins Medicine researchers conducting a small Phase II trial of the regimen, testing its safety and value.
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Molecular Target Identified for Treating Deadly Lung Disease
Scientists searching for a therapy to stop the deadly and mostly untreatable lung disease, idiopathic pulmonary fibrosis (IPF), found a new molecular target that slows or stops the illness in preclinical laboratory tests.
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Quartzy and Lab Launch Inc. Partnership to Help New Labs
Quartzy, a free online lab supply management and ordering platform, will now be made available to Lab Launch Inc. labs, which will provide new labs with software and equipment.
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Class of Drugs Could Help Tackle Treatment-Resistant Cancers
Researchers have discovered a new class of drug that has the potential to help cancer patients who no longer respond to existing therapies. The drug may not become available to patients for a number of years yet, but researchers believe that if clinical trials are successful, it could be used to tackle a variety of treatment-resistant cancers.
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Small-Molecule Structure Corrector Fixes Genetic Risk Factor for Alzheimer’s Disease
Using human brain cells, scientists at the Gladstone Institutes discovered the cause of—and a potential solution for—the primary genetic risk factor for Alzheimer’s disease, a gene called apoE4.
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Antiepileptic Drugs Increase Alzheimer’s and Dementia Risk
The use of antiepileptic drugs is associated with an increased risk of Alzheimer's disease and dementia, according to a new study from the University of Eastern Finland and the German Center for Neurodegenerative Diseases, DZNE.
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