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Bootlace Worm a New Source of Ion Channel Toxins
The longest animal in the world, the bootlace worm, which can be up to 55 metres long, produces neurotoxins that can kill both crabs and cockroaches.
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Ibuprofen Can Prevent Alzheimer's Disease -Apparently
A research team has successfully carried out studies suggesting that, if started early enough, a daily regimen of the non-prescription NSAID (nonsteroidal anti-inflammatory drug) ibuprofen can prevent the onset of Alzheimer’s disease.
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Fully Automated High-Throughput Sorting System Saves Time and Improves High-Throughput Screening
Breitwieser and colleagues of the Karlsruhe Institute of Technology (Germany) describe a fully automated high-throughput sorting system for zebrafish embryo phenotypes that benefits high-throughput screening by saving time and improving accuracy.
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Protein Nutrition for Cells and Organisms: Can We Use it to Treat Diseases?
In the April 2018 issue of SLAS Discovery, a review article highlights the demand for better inhibitors of amino acid transport processes and outlines promising new strategies and targets to develop amino acid transporters as drug targets.
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Prenatal Choline Intake Influences Fetal Development
Choline intake during pregnancy can influence infant metabolism and brain development, according to a series of studies. Although the role of choline in neurodevelopment has been studied before in rodents, the new research, done with pigs, has more relevance to humans.
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New Method Speeds Up Drug Development
One of the key steps in developing new drugs is determining the atomic structure of its biologically active substances. A research group has now modified a method that had previously been used exclusively for the crystallization of proteins, and successfully applied it to organic salts.
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Drug Could Stop Cancer-Causing Gene in its Tracks
Michigan State University scientists are testing a promising drug that may stop a gene associated with obesity from triggering breast and lung cancer, as well as prevent these cancers from growing.
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New Measures Announced to Stop Babies Being Exposed to Valproate in the Womb
New regulatory measures around sodium valproate, 'a landmark moment for all women who have ever been prescribed the epilepsy drug.'
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Western Diet Depletes Artery-Protecting Immune Cells
Scientists show how immune cells that shield arteries from inflammation are reprogrammed into cells that promote inflammation by high levels of fats and cholesterol.
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Swiss Army Knife of Protein Interactions
Researchers introduce an optimized and integrated approach combining affinity purification mass spectrometry and BioID in a single workflow for interaction proteomics. As they describe it, it proves almost as versatile as the Swiss Army Knife.
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