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Shaken and Stirred: Scaling Up Bioreactors’ Fluid Dynamics
By applying analytical techniques often reserved for large-scale industrial bioreactors to smaller lab-based counterparts, researchers are bridging the gap between different ways of mixing biomaterials.
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Hope for Hot Flushes: New Class of Menopause Drugs Reduces Severity
A new class of experimental drugs reduces hot flushes in menopausal women by almost three-quarters in just three days. The new analysis, published in the journal Menopause, also revealed sleep and concentration significantly improved in the three-day window.
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Study Debunks Fears of Increased Teen Suicide Risk From Tamiflu
Researchers from the University of Illinois at Chicago suggests that the drug oseltamivir - commonly known as Tamiflu - does not cause an increased risk of suicide in pediatric patients.
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Biomarkers to Personalize Treatment of Head and Neck Cancer
Researchers at A.C. Camargo Cancer Center in Brazil have found markers in the blood of head and neck cancer patients that can help identify cases that are likely to evolve to metastasis or develop local relapse after treatment.
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Drug-Delivery System Can Help Heal Even Without Drugs
A particular hydrogel, a self-assembling multidomain peptide (MDP) with the amino acid sequence K2(SL)6K2, is bioactive. Researchers found that even without additives their MDP is rapidly infiltrated by host cells, provokes a temporary inflammatory response, does not develop a fibrous capsule, supports the infiltration of a mature vascular network and recruits nerve fibers.
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Stress Cancer Cells to Death: Turning Off Autophagy Helps Chemotherapy
A University of Colorado Cancer Center study published today pinpoints a molecule that links autophagy and apoptosis, namely a transcription factor called FOXO3a. While researchers have known of the relationship between autophagy and apoptosis, what creates this link hasn’t been clear – in other words, we have known that turning off autophagy can help drugs push cancer cells into apoptosis, but we haven’t known how.
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Anti-Cancer Drug Could Reverse Social Deficits of Autism
Researchers reveal the first evidence that it may be possible to use a single compound to alleviate the behavioral symptoms of Autism by targeting sets of genes involved in the disease.
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Protein Structure Advances Diabetes and Parkinson's Research
The 3-D structure of a protein with links to several different areas of disease research has been detailed for the first time.
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Computing Power Aids Fight Against Food Poisoning
In a proof-of-concept study, researchers have pinpointed new compounds that may be effective in containing the virulence – or ability to produce disease – of Listeria, a well-known bacterium that can cause severe food poisoning and even death.
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New Way to Treat Aggressive Breast Cancer
Researchers have uncovered a way to treat aggressive tumours through manipulation of the connective tissue cells of the tumour. The researchers are now developing a new drug that transforms aggressive breast cancer so that it becomes responsive to standard hormone therapy.
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