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Drug Efficacy: Small Differences Cause Great Variation

Drugs are not equally effective for everyone. To some extent, this is due to the fact that people's bodies will take up a pharmaceutical substance to varying degrees. A group of researchers have now shed some light on the subject in their report published in the journal Cell Systems.
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This Virtual Yeast Cell Could Open Up The Black Box Of Artificial Intelligence

DCell is a virtual model of Baker's Yeast that could provide a greater understanding of the way AI functions.
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Best Disease Blindness Bettered By Gene Therapy

Best disease causes progressive loss of central vision and is currently incurable in humans. A new study which has reversed the effects in dogs using gene therapy may change that.
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Genetic ‘Seeds’ of Metastatic Breast Cancer Identified

Researchers have published their analysis of the genetic differences they discovered in patients' primary breast cancers and their metastatic cancers. By understanding how breast cancer metastases evolve, researchers hope to better explain how they occur. This insight could reveal new approaches in the treatment and prevention of metastatic breast cancer.
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Determining Structures For Large Proteins is Now Easier

Researchers have developed a new method of crystallising large membrane proteins in order to determine their structure. This will be of benefit to biological research and the pharmaceutical industry.
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Novel Method to Predict the Physical Stability of Drug Candidates

Researchers from the UK and Denmark have developed a new method to predict the physical stability of drug candidates, which could help with the development of new and more effective medicines for patients.
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Culturing Cheaper Stem Cells

A new combination of chemical compounds could lead the way to more cost-effective stem cell cultures.
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Synthetic Biology Breakthrough Means Bacteria Could Produce Our Essential Drugs

Bacteria could be programmed to efficiently produce drugs, thanks to breakthrough research into synthetic biology using engineering principles.
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Compounds Targeting Epigenetics Show Promise in Lymphoma Patients

New compounds targeting epigenetics have shown remarkable early activity in patients with lymphoma, according to data presented at the TAT (Targeted Anticancer Therapies) International Congress 2018.
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Metrion Biosciences Appoints Two New Board Directors

Metrion Biosciences Limited, the specialist ion channel contract research and drug discovery company, announced it has appointed Dr Barry Kenny and Dr Andrew Southan to its Board of Directors.
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