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Preclinical Safety in Cancer Drug Development: “Attitude to Safety Needs to Change”
Many companies involved in cancer drug research and development need to re-think their use of safety data in helping to bring new drugs to cancer patients.
Dr Richard Knight of ApconiX will tell this month’s conference, that greater focus on pre-clinical safety should be fundamental to the development of new cancer therapies.
Dr Richard Knight of ApconiX will tell this month’s conference, that greater focus on pre-clinical safety should be fundamental to the development of new cancer therapies.
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Molecular Atlas Maps Out the Blood Brain Barrier
The genes and structure of the diverse web of cells that supplies blood to the brain have been mapped in unprecedented detail.
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Researchers Test Drug Transfer Using Placenta-On-A-Chip
Researchers have demonstrated the feasibility of their "organ-on-a-chip" platform in studying how drugs are transported across the human placental barrier.
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'Click Chemistry' Reactions Could Boost Cancer-Fighting Drug Potency
Researchers at The Scripps Research Institute (TSRI) have developed a quick and easy way to simultaneously modify dozens of drugs or molecules to improve their disease-fighting properties.
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Psoriasis Drug Also Reduces Aortic Inflammation
An antibody used to treat the autoimmune skin disease psoriasis is also effective at reducing aortic inflammation, a key marker of future risk of major cardiovascular events.
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Neuromodulation of Behavior and Individuality Measured Over a Life-Time
Researchers illuminate the biology that guides behavior across different stages of life, and also suggest how variations in specific neuromodulators in the developing nervous system may lead to occasional variations.
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Stem-Cell Exosome Treatment Repairs Brain Damage Following Stroke
A team of researchers have developed a new treatment for stroke that reduces brain damage and accelerates the brain’s natural healing tendencies in animal models.
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Putting the Brain at the Center of Anesthesiology
Emery N. Brown explains how statistics and neuroscience improve anesthesiology at the American Association for the Advancement of Science's annual meeting.
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Computational Model Underlines Need for Personalised Approach to Sepsis
A computational model of the human immune system has enabled researchers to explore the challenges of tackling sepsis.
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Tiny Kidneys: Building Better Models to Test Drugs
A free online kidney atlas built by USC researchers empowers stem cell scientists everywhere to generate more human-like tiny kidneys for testing new drugs and creating renal replacement therapies.
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