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Study Points Way to Improved Stem Cell Therapies
Researchers have found that stem cell function can be enhanced through manipulation of their culture environment, and that "priming" prior to patient administration could optimize their therapeutic potential.
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Roles AKT Protein Family Identified
Researchers have identified the distinct roles and locations in the brain of a protein called AKT believed to be instrumental in memory formation.
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Testosterone: Why the Incidence of Multiple Sclerosis is Lower in Men
Researchers have discovered why men are much less likely to develop multiple sclerosis (MS) — high levels of testosterone. Testosterone triggers production of the cytokine IL-33 protecting them from the disease.
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Pharmaceutical Manufacturing Pollution Threatens Hyderabad
A new report highlights the serious environmental and human health impacts caused by uncontrolled manufacturing discharges from pharmaceutical factories in Hyderabad, India. These factories in Hyderabad constitute one of the world’s largest generic drug manufacturing hubs.
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Popular Medical Material Treated Like a Pathogen By Our Immune System
A study shows that our immune system handles graphene oxide (GO) in a manner similar to pathogens, paving the way for safer biomedical applications of this two-dimensional material.
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New Type of Botox Discovered
A new source of the botulinum neurotoxin was discovered by Canadian and American scientists in a strain of animal gut bacteria known as Enterococcus faecium. "Its discovery has implications in several fields, from monitoring the emergence of new pathogens to the development of new protein therapeutics--it's a game changer."
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Drug Target for Ewing Sarcoma Identified
Screening a class of recently-developed drug compounds -- so-called "CDK inhibitors" capable of blocking CDK7/12/13 proteins -- against hundreds of different human cancer cell lines, researchers have found that CDK12 inhibitors pack a particularly lethal punch to Ewing sarcoma.
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Zebrafish Are a Promising New Model For Autism Research
Research showed valproic acid exposure resulted in phenotypes and behaviors consistent with autism spectrum disorder, or ASD, and validated zebrafish as a model for studying ASD and its causes.
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Life-Saving Medicines Grow from Fundamental Chemistry
Prud’homme’s technology for encasing medicine in ultra-small particles had already led to new drug delivery approaches for high-value medical applications. The same process can now be adapted for large, continuous manufacturing.
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New Catalyst for Making Fuels from Shale Gas
Methane in shale gas can be turned into hydrocarbon fuels using an innovative platinum and copper alloy catalyst, according to new research led by UCL (University College London) and Tufts University.
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