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Oligonucleotide Drug Producers Report on Drug Impurities
A new addition to a series of articles that focus on important topics related to the development of oligonucleotide therapeutics presents an in-depth look at the identification, characterization, and reporting of product-related impurities.
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Tapeworm Drug Molecule Could Aid Fight Against Parkinson’s Disease
Researchers have identified a drug molecule within a medicine used to treat tapeworm infections which could lead to new treatments for patients with Parkinson's disease.
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Honey Bee Gut Metabolome Reveals How They Cope With a Pollen Rich Diet
The honey bee gut is colonized by specialized bacteria that help digest components of the floral pollen diet and produce molecules that likely promote bee health. Researchers studied the metabolome from the bee gut and have uncovered which bacterial species perform which specific digestive functions.
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Searching for the CRISPR Swiss-army Knife
High-resolution structural comparison of Cpf1 and Cas9 could help researchers achieve more accurate gene editing with CRISPR.
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IDEX Health & Science Announces Acquisition of New Microfluidics Company
IDEX Health & Science, LLC announced the acquisition of thinXXS Microtechnology that will accelerate growth of its microfluidics consumables business.
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BioGenes Establishes Scientific Advisory Board
BioGenes GmbH, specializing in ELISA development and production and a global leader in host cell protein (HCP) assay development, announces the establishment of a Scientific Advisory Board.
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Novel Isotope Tracking Method Offers Hope for Threatened Species
Locating even a single nest of the secretive goshawk required weeks of exploration. So scientists decided to conduct elemental analysis using strontium, which has naturally occurring isotopes found everywhere on Earth that travel the food chain from the soil to plants to herbivores and predators. Analysing prey remains enabled the researchers to determine where the birds of prey were hunting, findings that could help steer conservation efforts for goshawks and other vulnerable species.
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New Drug Successfully Treats Huntington Patients
The first drug targeting the cause of Huntington’s disease was safe and well-tolerated in its first human trial, and successfully lowered the level of the harmful huntingtin protein in the nervous system.
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Severity of Autoimmune Disease Influenced by Time of Day
Insights into how the body clock and time of day influence immune responses are revealed today. Understanding the effect of the interplay between 24-hour day-night cycles and the immune system may help inform drug-targeting strategies to alleviate autoimmune disease.
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Agent Reverses Resistance to Targeted Drug in Some Leukemias
After discovering how some hematologic cancer cells manage to elude death from a targeted therapy, Dana-Farber Cancer Institute scientists have double-crossed the cancer cells with a drug that renders them vulnerable to the targeted agent.
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