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After discovering how some hematologic cancer cells manage to elude death from a targeted therapy, Dana-Farber Cancer Institute scientists have double-crossed the cancer cells with a drug that renders them vulnerable to the targeted agent.

High vanadium concentrations have poorly documented but potentially negative consequences for human health. This study explores the biogeochemical cycle of vanadium including the contribution of human activities to the amount in the environment.

Scientists have now brought the family of LNM molecules even closer to clinical testing by “mining” the information stored in bacteria genomes. Their research suggests these hidden genes hold the blueprints for designing new, even more effective cancer-targeting compounds.

Scientists have developed novel lenses that enable X-ray microscopy with record resolution in the nanometre regime. Using new materials, the research team has perfected the design of specialised X-ray optics and achieved a focus spot size with a diameter of less than ten nanometres.

Scientists have proven the existence of an enigmatic new form of matter, which has perplexed scientists since it was first theorized almost 50 years ago - excitonium. This discovery was facilitated by using a novel technique they developed called momentum-resolved electron energy-loss spectroscopy.

The increasing access to healthcare facilities and the bolstering need for drugs to be used orally has been driving the consumption of generic drugs among people across the world, which, in turn, is fueling the need for controlled release technology for drug delivery to suffice the availability of drugs in small dosages.

Wildfires, cigarette smoking and vehicles all emit a potentially harmful compound called isocyanic acid. The substance has been linked to several health conditions, including heart disease and cataracts. Scientists investigating sources of the compound have now identified off-road diesel vehicles as a major contributor.

Scientists at DESY have developed a new method that enables automated and fast screening of promising drug candidates.

Most people agree that chocolate tastes great, but is there a way to make it taste even better? Scientists found that the weather had the largest effect on chemical composition. Overall, the antioxidant content increased and fat content of the beans decreased during the dry season as temperatures rose and soil moisture dropped. The researchers say these differences could contribute to variability in cocoa bean flavor.

New research suggests that administering taurine, a molecule naturally produced by human cells, could boost the effectiveness of current multiple sclerosis (MS) therapies. The discovery also highlights the potential for a technique called “metabolomic profiling,” which can identify useful endogenous metabolites the body already makes in small quantities, such as taurine, for new applications in drug therapies.