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Wildfires, cigarette smoking and vehicles all emit a potentially harmful compound called isocyanic acid. The substance has been linked to several health conditions, including heart disease and cataracts. Scientists investigating sources of the compound have now identified off-road diesel vehicles as a major contributor.

Scientists at DESY have developed a new method that enables automated and fast screening of promising drug candidates.

Most people agree that chocolate tastes great, but is there a way to make it taste even better? Scientists found that the weather had the largest effect on chemical composition. Overall, the antioxidant content increased and fat content of the beans decreased during the dry season as temperatures rose and soil moisture dropped. The researchers say these differences could contribute to variability in cocoa bean flavor.

New research suggests that administering taurine, a molecule naturally produced by human cells, could boost the effectiveness of current multiple sclerosis (MS) therapies. The discovery also highlights the potential for a technique called “metabolomic profiling,” which can identify useful endogenous metabolites the body already makes in small quantities, such as taurine, for new applications in drug therapies.

A team of researchers have made the first determination of the atomic structure of Transient Receptor Potential Melastatin 8. This finding should boost ongoing efforts by scientists to target TRPM8 therapeutically.

Supplementation with probiotics can improve a person's gut health, but the benefits are often fleeting, and colonization by the probiotic's good microbes usually doesn't last. Breast milk may help sustain those colonies in the long run.

A novel compound may restore immune response in patients with melanoma, according to a study presented at the ESMO Immuno Oncology Congress 2017.

A team led by researchers describe a new approach to prevent death in these essential kidney cells. Studying multiple animal models of kidney disease, the team discovered a compound that can impede loss of the filtration cells and restore kidney function.

Houston Methodist neuroscientist Robert Krencik, Ph.D., and his team have developed a new system to reduce the time it takes to grow these brain models, which will give them the ability to screen drugs and study what’s behind disease-causing mutations more quickly.

Novel antisense oligonucleotide interferes with the instructions for building the APOE protein and reduces pathophysiology of AD.