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Fewer Than Half of New Drugs Add Significant Therapeutic Value Over Current Treatments
According to a study, less than half of approved first indications for new drugs in the US and Europe between 2011 and 2020 add substantial therapeutic value over existing treatments.
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New Process Developed To Produce Ring-Shaped Molecules
For the first time, scientists have succeeded in using structural editing to insert a four-membered molecular ring into a larger, aromatic ring, creating a structurally complex bicyclic ring system.
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UK Government Agrees To Provide 10,000 Patients With Personalized Cancer Treatment
Ground-breaking new cancer treatments have moved a step closer with the signing of a major agreement between the government and BioNTech SE.
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ADHD Meds Administered During Childhood Are Not Associated With Later Life Substance Abuse
Children taking a prescription stimulant to manage symptoms of attention deficit hyperactivity disorder (ADHD) do not have more substance use or substance use disorder (SUD) as adolescents or young adults.
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Mechanism Revealed That Promotes Vulnerability of Cancer to a Form of Cell Death
A specific mechanism is able to promote cell death in cancer cells by pharmacological targeting of a ferroptosis surveillance system.
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New Drug Discovery Platform Could Target a Slew of Diseases
The comprehensive screening platform and cellular interrogation tool has the potential to facilitate novel drug discovery targeting a slew of human diseases.
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First Gene Therapy for Hemophilia A Approved in the US
Roctavian (valoctocogene roxaparvovec) has become the first ever gene therapy for adults with severe haemophilia A to be approved by the FDA.
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African Mosquito Suppression System Could Halt Malaria Spread
Researchers have engineered a new way to genetically suppress populations of the mosquitoes that primarily spread malaria in Africa.
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Paracetamol Can Be Made From Pine Trees Instead of Crude Oil
A team of scientists have found a way to create two of the world’s most common painkillers, paracetamol and ibuprofen, out of a compound found in pine trees, which is also a waste product from the paper industry.
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Breast Cancer Treatment Time Cut by a Week With Radiotherapy Boost
Treatment times for radiotherapy could be reduced for some early breast cancer patients, according to a trial
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