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Next-generation Optogenetic Molecules Used to Control Single Neurons

The focused laser beam could help scientists map connections among neurons that underlie behavior.
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Virus vs Human: Gene Similarities Offer Cellular Defense Insights

Scientists have found that a key similarity between our genes and those of many viruses—a way of spelling out the genetic code – has likely allowed viruses to evade our cellular defenses. The research offers insight into novel avenues for vaccine development.
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Discovering a Protein’s Role in Gene Expression

Beyond providing new insights into the regulation of gene expression, the findings have important implications for metastatic melanoma, and several neuro-developmental syndromes.
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Body Clocks Cause Wounds Sustained at Night to Heal More Slowly

A new study has discovered how our body clocks cause wounds, such as cuts and burns, to heal approximately 60% faster if the injury happens during the day rather than at night. This could have implications for medical procedures such as surgery and provides targets for developing drugs that improve wound healing
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Innovative Genetic and Cellular Techniques Help Identify Multiple Disease Targets

CRISPR-Cas9 and iPSC advances hold treatment promise for schizophrenia, addiction, Zika infection and other diseases. The studies were presented at Neuroscience 2017, the annual meeting of the Society for Neuroscience
Obese and Anorexic Women Have Low Levels of ‘Feel Good’ Neurosteroid content piece image
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Obese and Anorexic Women Have Low Levels of ‘Feel Good’ Neurosteroid

Researchers have found that women at opposite extremes of the weight spectrum have low levels of the neuroactive steroid allopregnanolone, a metabolite of the hormone progesterone. Gas chromatography and mass spectrometry were used to pick up extremely small levels of these chemicals in blood serum, saliva and brain tissue.
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Quotient Sciences Launches as the New Global Identity for Quotient Clinical

Quotient is focused on delivering a portfolio of innovative services encompassing formulation development, clinical trial and commercial manufacturing, and clinical pharmacology.
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Recipe to Make Human Blood-brain Barrier Created

A team of UW–Madison researchers has developed a tightly defined, step-by-step process to turn multipurpose stem cells into the cells that make the human blood-brain barrier, the anatomical feature that protects our brain from toxins and other threats that may be in circulating blood.
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Potential Biomarker for Early Detection of Alzheimer's

Findings may also provide a means of homing drugs to diseased areas of the brain to treat AD, Parkinson's disease, as well as glioblastoma, brain injuries and stroke.

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AbVance Project: Antibody Structures Released into Protein Data Bank

The Pistoia Alliance, a global, not for profit alliance that works to lower barriers to innovation in life sciences R&D has announced today that its project to increase knowledge of antibody (Ab) structures has reached its first major milestone – 12 antibody structures have been deposited into the European Bioinformatics Institute’s (EMBL-EBI) Protein Data Bank (PDB).
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