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AI Model Can Design Millions of New Superbug-Fighting Antibiotics

The spread of drug-resistant bacteria has created an urgent need for new antibiotics. Researchers report that they have developed a new generative AI model that can design new antibiotics to stop the spread of one of the world’s most dangerous antibiotic-resistant bacteria.

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Early Intervention Post-Seizure May Prevent Long-Term Epilepsy

According to research, an experimental treatment can prevent long-term changes to neurons seen in epilepsy if provided within the first two days after the first seizure.
Orange and white pill capsules spill from a prescription bottle.
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Pill May Improve Muscle Strength in Myasthenia Gravis, Study Finds

A new pill could improve muscle strength for people with myasthenia gravis, a rare autoimmune condition.
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Innovative Platform for Targeting Protein Stability in Disease Treatment

Using a newly created platform, researchers have interrogated the entire human proteome for "effector" proteins, which can influence the stability of other proteins via induced proximity. The scientists were able to identify many new effectors with possible therapeutic uses.
Histology of ovaries from healthy mice vs. mice without Usp7 gene.
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Researchers Uncover Protein Networks in Female Mouse Reproduction

Scientists have found that while a protein called FOXL2 plays a role in embryonic development, it regulates the activity of many more genes after birth.
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Protein Evolution Research Could Open Path to Drug Diversity

Many important medicines, such as antibiotics and anticancer drugs, are derived from natural products from Bacteria. By exploring protein evolution, a team has found new "fusion sites" that enable faster and more targeted drug development.
A plastic model of a kidney held in a person's hand.
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Living Recipient Receives World's First Genetically-Edited Pig Kidney Transplant

The world's first gene-edited pig kidney transplant has been successful, reports Massachusetts General Hospital. The procedure marks a major milestone in the quest to provide more readily available organs to patients.
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Using Contact Lenses To Heal Eyes Faster

A cross-disciplinary University of Waterloo team has developed a new contact lens material that could act as a bandage for corneal wounds while releasing drugs in a controlled manner to help the eye heal faster.
A syringe with pale pink liquid rests on two empty syringes.
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Gene Therapy for Rare Neurodegenerative Disease Shows Promise in Trial

An investigational gene therapy for a rare neurodegenerative disease that begins in early childhood, known as giant axonal neuropathy, was well tolerated and showed signs of therapeutic benefit in a clinical trial.
A blue-green pill in the middle of white tablets.
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Discovery May Reduce Dependence on Animals for Anti-Clotting Drug

Researchers have developed a process to bioengineer heparin, the world’s most widely used blood thinner, which is currently derived from pig intestines.
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