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Study Investigates the Function of Autoimmune Disease Drug Currently in Clinical Trial
Researchers have revealed the structure and function of a drug which can reduce the harmful activity of the immune system to help treat autoimmune diseases, and is currently in a Phase 2 clinical trial for lupus.
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Chest Pain Medication Trial for Hot Flashes Finds Only Short-Lived Benefits
Researchers have found that for menopausal women, continuously wearing a nitroglycerin patch provided short-term improvements in moderate to severe hot flashes but the benefits did not extend past 12 weeks.
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Study Uncovers Mode of Action of New Type 2 Diabetes Drug
Tirzepatide is a recently approved treatment for type-2 diabetes. Treatment with tirzepatide decreases body weight while improving glucose metabolism in patients with obesity and type-2 diabetes.
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Study Shows How Psychedelic Drugs Rewire the Brain
A new study has revealed details about how the psychedelic drugs LSD and psilocin – the active ingredient in magic mushrooms – bind to receptors in the brain.
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Clinical Trial Leads to Advances in Treatment for Glioma Patients
In the phase 3 INDIGO clinical trial, vorasidenib significantly prolonged progression free survival and delayed radiation and chemotherapy for patients with Grade 2 IDH-mutant glioma.
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Immunotherapy Discovery Could Help Prevent Breast Cancer From Spreading
Two new discoveries highlight the different roles of blood vessels in solid tumors – and the findings could help prevent breast cancer from spreading and enhance the effectiveness of one of the most important new cancer treatments in many years.
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Pathogenic Mosaic Mutations Linked to Bipolar Disorder Discovered
Researchers find a link between bipolar disease and potentially pathogenic mosaic mutations found in neurodevelopmental disorder genes and mitochondrial tRNA genes.
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Oral Estrogen Hormonal Therapy May Increase Risk of High Blood Pressure
According to research, women 45 and older taking estrogen hormone therapy in pill form were more likely to develop high blood pressure than those using transdermal or vaginal formulations.
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Potential Drug Target Identified for Infection, Inflammation and Hemolytic Diseases
Researchers have found a key ‘on’ switch, called NLRP12, for innate immune cell death in diseases that cause red blood cells to rupture, which can lead to inflammation and multi-organ failure.
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High Blood Pressure Treatment for Hospitalized Patients Linked to Heart and Kidney Injury
This study highlights the need for further study of best practices for management of hospitalized patients.
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